I am the Director of Marketing and Business Development for Bioo Scientific, an Austin-based biotech company that offers products and services in the following areas:
Food and Feed Safety Products
Bioo Scientific is a market leader in the food and feed safety testing industry. We develop, manufacture and market a wide range of food and feed safety products for the detection of microbial and industrial contaminants, natural toxins, and veterinary drug residues.
Life Science Products
Bioo Scientific offers a wide range of products to facilitate life science and preclinical research. In addition to our innovative RNAi delivery solutions, our rapidly expanding product line includes gene-specific cytokine ELISAs, toxicology testing assays, tools for working with small RNAs, and kits which simplify DNA and RNA isolation and PCR and protein detection.
Services
Bioo Scientific has the experience and expertise to help you successfully complete preclinical drug development by designing, performing, and documenting safety tests that meet regulatory requirements. A few of the services that our highly trained scientific staff provides include in vivo RNAi/miRNA, immunohistochemistry, monoclonal antibody and protein and animal services at our USDA and OLAW approved animal facility.
I also co-own and moderate, Austin FreeCycle, an online free recycling group with over 16,000 members.
Follow me on Twitter @dobermoeller1 or follow Bioo Scientific at @biooscientific.com
Parental 5-methylcytosine methylation patterns are stable upon inter-species hybridization of Xiphophorus (Teleostei: Poeciliidae) fish.
Description of Article:
Cytosine methylation appears to be established as an important DNA base modification involved in regulation of gene expression but is poorly understood from an evolutionary viewpoint. Xiphophorus progeny from inter-species crosses and backcrosses that are utilized in contemporary tumor induction studies were analyzed for cytosine methylation pattern inheritance using Southern blot analyses. Methylation patterns at CCGG sequences of 411 independent chromosomes in three distinct inter-species crosses were analyzed. In every case the non-recurrent parental methylation pattern remained unaltered for each of the genes studied, once introduced into the recurrent parental genetic background. Through F(1) inter-species hybridization and succeeding meiosises leading to first generation (BC(1)) and second generation (BC(2)) backcross hybrid progeny, we demonstrate that parental species methylation patterns are stable.
Relative Base Excision Repair in Xiphophorus Fish Tissue Extracts
Description of Article:
To begin characterizing DNA repair capability among Xiphophorus species, we adapted oligonucleotide-based DNA repair assays to extracts of fish tissues.
Armored RNA technology for production of ribonuclease-resistant viral RNA controls and standards.
Description of Article:
We describe the development of a versatile, novel system for creating RNase-resistant RNA. "Armored RNA" is a complex of MS2 bacteriophage coat protein and RNA produced in Escherichia coli by the induction of an expression plasmid that encodes the coat protein and an RNA standard sequence.