Associate Principal Scientist, Merck & Co.
Fengqiang Wang, Ph.D., is currently an Associate Principal Scientist and Technical Lead in the Biologics Analytical Method Development Group of Merck Research Laboratories (MRL). He started at Merck in 2011 as a senior scientist working on the biochemical characterization of biologics and biosimilar similarity study with originator using a variety of analytical tools such as N-glycan analysis and peptide mapping. Then a major part of his work focused on the development of process- or platform-specific residual host cell protein (HCP) ELISA to support HCP impurity testing in Biologics, including marketed products such as Keytruda and Zinplava. Other than immunoassay development, he also worked on extensive detection and characterization of HCPs and anti-HCP reagents in biologics with 1D/2D SDS-PAGE, 2D-DIGE, 1D/2D-Western blot and 1D/2D-LC-MS. In addition, he is also specialized in assay development for monitoring other process residuals such as protease inhibitors, trypsin, MSX, β-glucan etc. He has authored more than 40 peer-reviewed scientific publications and presented at many national and international meetings including AAPS annual meeting, BEBPA HCP Annual Conferences from 2015 to 2018, BPI, and CHI's Bioprocessing Summit HCP Conference from 2016 to 2017. He also authored several book chapters on antibody engineering and ovarian cancer and had two patents on antibody drug conjugates.
Before Joining Merck, Dr. Wang had devoted almost a decade of his career in ovarian cancer research in the National Ovarian Cancer Early Detection Program run by Dr. David A. Fishman, starting as a post-doctoral researcher in Northwestern University and later on becoming an Assistant Professor in New York University School of Medicine. Dr. Wang received his Ph.D. in Cancer Pharmacology (Microbial and Biochemical Pharmaceuticals) from Peking Union Medical College & Chinese Academy of Medical Sciences in 2002 and had a Master degree in Medicine and Bachelor degree in Pharmacy.