MAY 02, 2016 8:00 AM PDT

Clinical use of coagulation tests: Thrombophilia testing, D-dimer use, DOAC level testing

Sponsored by: Diagnostica Stago, Inc.
  • Professor of Medicine, UNC-Chapel Hill Hemophilia & Thrombosis Center
      Dr. Moll received his medical degree from Freiburg University, Germany, He completed an internship/residency in internal medicine and a hematology-oncology fellowship at Duke University Medical Center (1989-1996), during which he also did a 1-year clinical coagulation fellowship at the University of North Carolina, Chapel Hill (1994-1995). Dr. Moll's postgraduate career included a position in clinical coagulation in the cardiology division of the Humboldt University in Berlin, Germany (1997-1999). Dr. Moll has been a faculty member at UNC in the Department of Medicine and the Division of Hematology-Oncology since 1999. His clinical focus is coagulation, particularly thrombosis and thrombophilia. Dr. Moll's research interests include clinical trials on new anticoagulants, better use of established anticoagulants, antiphospholipid antibody syndrome and postthrombotic syndrome. He has a major interest in health education of patients, public and health care providers about blood clots and clotting disorders. Since 2001 he has written a Q/A section on thrombosis and thrombophilia for the non-profit website Dr. Moll is a co-founder of the national patient advocacy group NBCA (National Blood Clot Alliance;, and a board member of the national non-profit anticoagulation provider organization AC-Forum (Anticoagulation Forum; He has authored and coauthored a number of peer-reviewed articles textbook chapters on blood clots. He is the founder of the UNC Blood Clot Education Outreach Program created in 2010.


    This webinar will discuss the influence of anticoagulants on laboratory testing results for thrombophilia and appropriate testing situations for patients suspected of thromboembolism. In addition, we will review published data on D-dimer as a predictor for recurrent VTE and the use of D-dimer for VTE management. Last, the role of DOAC tests in the above applications will be covered.

    • Discuss situations where venous or arterial thromboembolism thrombophilia testing is appropriate.
    • Recognize how anticoagulants influence thrombophilia test results.
    • Discuss the published data on D-dimer as a predictor for recurrent VTE, and how to appropriately use the D-dimer for VTE management decisions.
    • Understand and make decisions about which patients on a direct oral anticoagulant (DOAC) might benefit from anticoagulant testing, what test to use, what DOAC level to expect, and how test results influence patient management.
    • Evaluate the right testing strategy for LA testing.
    • Correlate LA and APS to specific clinical cases.

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