APR 02, 2012 8:00 AM PDT

D-dimer in the Management of Venous Thromboembolism

Sponsored by: Diagnostica Stago, Inc.
  • Professor Department of Medicine, Adjunct Professor Department of Radiological Sciences, College of Medicine University of Oklahoma Health Sciences Center
      Suman Rathbun, MD is currently Director of the Vascular Medicine Program at OUHSC as well as director of the vascular laboratories and vascular fellowship at OU Medical Center, Oklahoma City, Oklahoma. Dr. Rathbun has been principal investigator in several research projects regarding pulmonary embolism and deep-vein thrombosis. Dr. Rathbun has published and presented both locally and nationally. She participated on the U.S. Surgeon General's task force for awareness of deep-vein thrombosis in Washington, DC. Currently, she serves as secretary to the Society of Vascular Medicine and chair of the education committee for the Venous Disease Coalition. Suman Rathbun received her doctorate of medicine at the University of Texas at San Antonio, Texas in 1994. Dr. Rathbun received her master's degree in epidemiology at the University of Oklahoma Health Sciences Center in 2004. She is board certified in internal medicine and vascular medicine.


    Venous thromboembolism (VTE) is a serious prothrombotic disease state caused by acquired or inherited factors and is responsible for a high rate of morbidity and mortality.  Deep venous thrombosis (DVT) and pulmonary embolism (PE) refer to VTE located in the deep veins or lungs, respectively.  Diagnostic strategies for identification of VTE, DVT, and PE include imaging as well as laboratory testing methodologies such as the D-dimer assay.  The purpose of this educational activity is to review clinical decision rules, case studies, and the role of the D-dimer assay in the diagnostic management of VTE.

    • Recognize venous thromboembolism: deep-vein thrombosis and pulmonary embolism and its consequences.
    • Discuss the use of D-dimer in the exclusion of patients with clinically suspected first-episode or recurrent deep-vein thrombosis.
    • Discuss the utility of D-dimer in the determination of length of anticoagulation after first-episode deep-vein thrombosis.

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