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Fifteen years ago we (my colleague and daughter, Sarah-Ellen Perkins Leonard) began a private quest to assess basic protein activity. Now, over a decade later, our efforts culminate in fundamentally new approaches - approaches deemed "revolutionary" by an NIH reviewer - to assess both protein interactions and protein degradation.
These are broad, sweeping, new (proprietary) methods capable of detecting and characterizing protein interactions and degradation events on intact proteins in media of any complexity. The potential in phenotypic drug target development and drug candidate screening is enormous.
Couple these developments to my personal experience in assessment of disease states, diagnostic methods development and drug testing in animal models of neuromuscular disease.
I also bake a pretty mean loaf of bread.
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