How do recombinant lentivirus systems work?
➜ Recombinant lentivirus systems are powerful tools for gene delivery and gene therapy. Because they can stably integrate transgenes into the host genome, they are unique tools for generating stable cell lines for long term expression. As they have broad tropism and can infect both dividing and non-dividing cells, recombinant lentivirus systems enable delivery of transgenes into any tissue type. In this video we will introduce you to the basic structure and genome map of the HIV Lentivirus and explain the differences and advantages of using first, second, and third generation recombinant lentivirus systems.