Anti-Xa for Monitoring Heparin

Anticoagulants are effective for prevention and treatment of prothrombotic disease states and can be prescribed for parenteral (IV) or oral administration.  Several novel, direct acting oral anticoagulants (abbreviated as NOACs or DOACs) have been introduced over the past few years.  A review of anticoagulant therapy approaches and indications will be provided along with recommended methods for monitoring and/or activity measurement; including a comprehensive discussion of how the different assay methods are affected by various pre-analytical, analytical, and biological states.

• Compare traditional anticoagulants to novel oral anticoagulants (NOACs).
• Discuss the differences between the NOACs.
• Evaluate methods for monitoring traditional anticoagulants and measuring activity of NOACs.
• Discuss potential anticoagulant assay interferences.