Physiologic medium to study human cell biology

Jason earned his B.S. magna cum laude in Chemical Engineering from Cornell University and then completed his Ph.D. in Chemical Engineering from The University of Texas at Austin. Under the guidance of George Georgiou, Jason's doctoral work focused on developing new strategies to engineer anti-cancer therapeutic enzymes with reduced immunogenicity and was supported in part by a graduate fellowship from the US Department of Homeland Security. Jason then completed his postdoctoral training in the laboratory of David M. Sabatini at the Whitehead Institute/MIT. During that time, his work focused on investigating how environmental factors impact cancer metabolism and involved creating the first systematically designed physiologic medium (human plasma-like medium; HPLM) among other new tools. This work was supported in part by fellowships from both the American Cancer Society and the Koch Institute for Integrative Cancer Research at MIT. Jason then launched his independent program as an Investigator at the Morgridge Institute for Research with joint appointment as an Assistant Professor of Biochemistry (with affiliate status in Biomedical Engineering) at the University of Wisconsin-Madison and membership in the Carbone Cancer Center. Thermo Fisher Scientific is proud to work with Jason and David in bringing HPLM to market, and excited by the immense possibilities that it could bring to diverse areas of the scientific community. Jason and David are inventors on a patent application for HPLM assigned to Whitehead Institute.