mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield and high‑quality products. This 15-minute webinar discusses the material quality attributes and the process considerations that are required to successfully synthesize mRNA using in vitro transcription. It also covers the important factors that go into scaling‑up the production of mRNA‑based therapies.

Learning objectives:

1. Recognize the importance of raw materials in mRNA production.

2. Discuss quality attributes of mRNA raw materials.

3. Review considerations for mRNA synthesis and scale‑up.