OCT 27, 2016 9:00 AM PDT

Achieving Reproducibility: Don't Let Antibodies be a Variable in Your Experiment

  • Scientific Project Manager, Cell Signaling Technology
      Dr. Couvillon has worked at Cell Signaling Technology, Inc. for almost ten years. He joined the company as a product development scientist where he oversaw the validation and release of over 100 different antibody products. Dr. Couvillon also lead a team responsible for the generation of antibodies and kits used for enrichment and analysis of post-translational modifications. He currently works as a special project manager in the marketing group where he is committed to guiding CST's adherence to antibody validation standards and practices. He has been active in attending and presenting at major meetings regarding the topic of antibody reproducibility and works with subject matter experts, antibody users and CST's scientists to ensure that CST continues to lead the field in antibody quality and consistency.

    DATE:  October 27, 2016
    TIME:  9:00am PT, 12:00pm ET

    The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasingly come under fire for their lack of reproducibility. Part of the issue is that the antibody market is composed of hundreds of vendors and resellers with varying definitions for validation and consistency. Cell Signaling Technology (CST) believes that antibody suppliers should be held accountable for the products they provide, but that vendors alone cannot solve the reproducibility “crisis”. How antibodies are validated and used in the laboratory is a critical component to this process. Researchers need to be more attentive to following established protocols and leverage the expertise of the scientists who have developed and tested the product they are using. Journals need to be more active in enforcing existing policies regarding materials and methods or develop more clear-cut means to identify and describe the use of biological reagents in published research. During this webinar we will address the role vendors, researchers, and journals should play in minimizing irreproducibility. We will also outline CST’s antibody validation process, while highlighting steps all users should consider when selecting and using antibodies in their research.

    Learning Objectives
    • Understand the importance of antibody validation and what roles vendors, researchers, and journals play in minimizing irreproducibility.
    • Learn what steps to consider when selecting and using antibodies for research.

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