Chairman Emeritus of Pathology, Cedars Sinai Medical Center - Clinical Professor of Pathology, UCLA - Adjunct Professor of Pathology, Northwestern University
BIOGRAPHY
MAY 13, 2020 8:00 AM PDT
Coronavirus Disease 2019 (COVID-19): Role of Serologic Testing in Diagnosis and Assessment of Viral Immunity
Speaker
Abstract
- Provide education on COVID-19 disease and SARS-CoV-2.
- Review the types of tests used for the diagnosis of infectious diseases.
- Discuss approaches to serologic test development.
- Review the kinetics of the antibody response and the functions of immunoglobulin subclasses in the immune response and analytes for monitoring immunity to a pathogen (SARS-CoV-2)
- Discuss pros and cons in measuring virus-specific IgG vs IgG+IgM.
- Discuss the functions of the SARS-CoV-2 proteins commonly employed in serologic assays—Nucleocapsid Protein and Spike Protein.
- Review the differences and similarities of diagnostic antibodies and neutralizing antibodies.