APR 14, 2020 9:00 AM PDT

Gibco Cell Culture Heroes: Work From Home Edition

  • Research Affiliate, Postdoctoral, Roswell Park Cancer Institute
      "I completed both a Bachelors in Sciences in Molecular Genetics and a Bachelors in Arts in English with a concentration in Theater at the University of Rochester in 2009, graduating Magna Cum Laude with election to Phi Beta Kappa. I then immediately began my PhD graduate training in Pathology at the University of North Carolina at Chapel Hill, defending my dissertation in 2014, in less than 5 years.

      I published 7 manuscripts based on my dissertation work, 4 of which are first-author, on the ubiquitin proteasome system in cardiac and skeletal muscle diseases. Specifically, my work focused on muscle atrophy-associated ubiquitin ligases that regulate nuclear receptor transcription factors in cardiac hypertrophy. My dissertation work was funded by a Predoctoral grant awarded to me by the American Heart Association. In addition, I have given several oral presentations at national meetings on this topic, for which I received trainee travel grants from both the American Society for Investigative Pathology and American Physiological Society.

      I came to Roswell Park Cancer Institute in January 2015, joining the laboratory of Dr. Shahriar Koochekpour to study the mechanisms governing castration-recurrent prostate cancer. Recently, I have published three comprehensive review articles on treatment of advanced prostate cancer and therapy resistance and a research article on how the FDA-approved drug for ALS , riluzole, has anti-tumor effects in prostate cancer. In September 2016, I joined the laboratory of Dr. David Goodrich to study the mechanisms driving neuroendocrine prostate cancer. I presented my current work as a podium presentation at the 2018 Annual Meeting of the American Association for Cancer Research.

      Being a first-generation student, I am dedicated to community outreach. Especially in teaching young students with similar backgrounds about opportunities in science, technology, engineering, and math (STEM)."
    • Research Associate, University of Cincinnati, Department of Internal Medicine, Division of Nephrology, Cincinnati OH
        Ameet is currently a Research Scientist in Dr. Laura Conforti's laboratory at the University of Cincinnati, where he studies the role of ion channels in T lymphocyte function, primarily in the context of solid tumors. He obtained his degree in Medicine from the University of Nagpur, India and completed his doctoral training where he studied ion transport physiology in disease causation under the guidance of Dr. Peter Lauf at Wright State University in Dayton Ohio. Subsequently, Ameet joined Dr. Conforti's laboratory as a postdoctoral fellow where he optimized the methodology for isolating tumor infiltrating lymphocytes from head and neck squamous cell tumors and developed various flow cytometry and microscopy based assays to detect ion channel function in blood and biopsy specimens from cancer patients. Ameet then transitioned to the position of Research Associate in Dr. Conforti's laboratory in 2015 and was promoted to the position of Research Scientist in 2019. He is currently continuing with his translational research. In addition to his research responsibilities in Dr. Conforti's laboratory, Ameet is also passionate about mentoring young STEM students in the laboratory and about science communication and outreach. You can follow Ameet's personal twitter @ameetchimote and learn more about the research done at the Conforti Lab at the University of Cincinnati at med.uc.edu/confortilab
      • Postdoctoral Fellow Department of Physiology, Louisiana State University Health Sciences Center
          My passion for science started at a very young age. My dad was a forensics investigator for the New Orleans police department & after school I would spend time in the lab where he taught me about DNA, fingerprints, & microscopy. I was fascinated by the puzzle of all of it and I made my life goal to be an "ist" (scientist, biologist, paleontologist, etc.). My teachers & professors encouraged my love of science & made sure to emphasize the contributions of women in science, like Marie Curie, Rosalind Franklin, & Barbara McClintock. I admired the sacrifices these women made in order to help humanity & advance their fields.
          I received a scholarship to attend Randolph College where I received a bachelor's of science in Biology & Psychology with a pre-med concentration. There I learned the value of experiments & research from the best professors I have ever met, & was encouraged to pursue a career in research. I was then accepted to Tulane University School of Medicine where I received my PhD in Biomedical Sciences with a concentration in Microbiology/Immunology in 2019. I completed my degree at Tulane National Primate Research Center under the guidance of Dr. Marcelo Kuroda, Dr. Woong-Ki Kim, & Dr. Andrew MacLean. My dissertation focused on the neuroimmunology & neurovirology of HIV-Associated Neurocognitive Disorders in a simian model, with emphasis on macrophages of the central nervous system, the choroid plexus (blood-CSF barrier), & inflammaging. One of my key projects was the creation of a primary rhesus macaque choroid plexus cell culture for use studying the effects of inflammation on the blood-CSF barrier.
          Currently, I am a Postdoctoral Research Fellow at LSU Health Sciences Center where I work in the Physiology Department in Scott Edwards Lab studying the neurobiological interactions of alcohol, opioids, & pain in rat & simian models. In my free-time I love to spend time with my two dogs, Wishbone & Thor, & going on adventures to try new food with my husband.
        • Postdoctoral Research Fellow, Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School
            Daisy Shu received her BOptom and BSc degrees from the University of New South Wales (UNSW) Sydney, Australia in 2012. She then worked in clinical practice for two years before starting her PhD in Ophthalmology at the University of Sydney, Australia under the supervision of Professors Frank Lovicu and John McAvoy. Her research explored growth factor signalling pathways activated during the formation of fibrotic forms of cataract with a focus on transforming growth factor-beta (TGFβ)-driven epithelial-mesenchymal transition. She is currently a postdoctoral research fellow at Schepens Eye Research Institute, Harvard Medical School, Boston, MA in the Magali Saint-Geniez Labotary studying the role metabolism and mitochondrial in retinal eye diseases with a focus on the role of TGFβ.

            Daisy currently serves on the Association for Research in Vision and Ophthalmology (ARVO) Advocacy and Outreach Committee (since 2018), Harvard Medical School Postdoc Association and Young Investigator Committee of the International Society for Eye Research (ISER). Daisy has presented at numerous local, national and international conferences including ARVO, ISER and the American Academy of Optometry Annual Meeting. She is a recipient of American Academy of Optometry 2018 Irvin M. Borish Ezell Fellow, The University of Sydney John Irvine Hunter Prize for best publication in 2018, Australian Society for Medical Research (ASMR) 2017 Best Student Oral Presentation Prize and the ARVO 2016 Members-in-training Poster Prize in Lens.

            Daisy is passionate about science communication and outreach. She was part of the first cohort to complete the ARVO Science Communication Training Fellowship in 2017. She is a co-host of "The Peer Review", a podcast about science, research and academia. She successfully crowdfunded her PhD research project on Experiment.com in 2017 on curing cataract.

            She enjoys updating her followers on her science adventures on social media via the handle @EyeDaisyShu.
          • Post Doctoral Associate, Florida International University
              Dr. Vivek Kamat received his Ph.D. from the University of Pune (India) in 2018. During his doctoral training under the supervision of Dr. Kishore Paknikar and Dr. Dhananjay Bodas at Agharkar Research Institute (Pune, India), he mastered the size-controlled synthesis of a variety of nanoparticles and the process of soft lithography fabricating complex microstructures using natural and artificial polymers. His work involved the size-controlled synthesis of drug-loaded nanoparticles and assessing their biological effect on cancer cell lines. Further Dr. Kamat worked in the area of tumor microenvironment specifically understanding cellular response and growth in confined volumes. He has experience in modeling and simulating biological system Insilco using COMSOL to study fluid dynamics, particle transport, and heat transfer. Dr.Kamat has experience working in interdisciplinary areas involving Cell biology, Nanotechnology, Electronics, and Microfabrication.

              Dr. Kamat joined the laboratory of Professor Shekhar Bhansali at Florida International University Department of Electrical engineering (FIU, Miami, USA) where he is working on understanding circulating tumor cells using electrical and optical methods to investigate cell-cell interactions and tumor microenvironment. He is also involved in integrating Artificial Intelligence and Machine learning to understand and predict cancer progression. He has active collaboration with Professor Kalai Matee at the Herbert Wertheim College of Medicine (FIU) working on transcriptomics analysis of cells growing in continuous flow conditions in microfluidic devices and along with his research he is involved in active teaching at the undergraduate level at FIU College of Engineering.
            • Research Fellow, Michigan State University
                My name is Sandra Hammer. I am a postdoctoral fellow in the Busik Laboratory at Michigan State University. Prior to being at MSU, I attended Vanderbilt University where I obtained my PhD in Cell and Developmental Biology under the mentorship of John Penn. Prior to this, I got my BS degree from the University of Miami.
                Scientifically, I am interested in the role that cholesterol metabolism and inflammation play in progression of microvascular disease. I am specifically interested in diabetes-induced retinal diseases. I am currently working on elucidating the role that the SIRT1/LXR signaling pathway plays in retinopahty progression. I have discovered the novel involvement of this pathway in preventing disease progression and am very interested in strategies that increase SIRT1/LXR signaling. My long term goals are to develop a energetic and productive independent research program well suited to investigate lipid dysregulation in microvascular complications.

              DATE:  April 14, 2020
              TIME:   9:00am PT, 12:00pm ET
              Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Elizabeth, Daisy, Ameet and Kristine all have in common? They are all stuck at home following "stay at home" guidelines, trying to stay connected with their research and labmates but also family and friends. During this webinar, they will share their best practices of being productive, staying connected, keeping a healthy outlook while out of the lab. Don't miss out on this webinar designed to help you navigate working from home and staying connected.
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