We will discuss the Digital LightCycler System, a digital PCR (dPCR) system for DNA and RNA with 6-color capability for flexible, multiplexed biomarker detection.  With advances in sensitivity, precision, flexibility, and integration, the Digital LightCycler System is a powerful digital PCR system that aims to help laboratories push the boundaries of clinical research forward.  Three configurations of consumables are available to meet varied application needs, including high sample volume for cfDNA screening or greater number of partitions for high-resolution CNV analysis.  We will present data that demonstrates the sensitive performance of the Digital LightCycler System as the powerful new addition to the Roche PCR ecosystem.