DATE: November 16, 2017
TIME: 12:00PM PT

Automating complex workflows that require manipulating or assessing samples over days or weeks often require thinking beyond a liquid handler.  The benefits of integrating additional storage devices and analyzers can occur on two broad levels.  At the sample level, the physical integration of devices with the liquid handler can remove the need to manually interact with each plate, thereby reducing the effort required for higher sample throughput while also reducing the potential for human errors.  At the data level, sample processing and analyzer data can be immediately linked to ensure no errors are introduced during data deconvolution.  In addition, this data can be used to directly drive the liquid handling on an integrated system.  We will describe how these benefits can apply to an integrated cell line development process that involves the plating, expansion, and screening of single cell-derived colonies to establish a protein-expression cell line.

Learning Objectives:

• How physically integrating storage and analyzer devices to a Biomek Workstation can reduce the workload and errors with higher throughput applications.
• How automated data integration can reduce errors in data handling throughout a complex or multi-day workflow
• How data-driven pipetting can automate steps such as hit picking without manual intervention