JAN 29, 2020 9:30 PM PST

Significance of Mean Cell Hemoglobin of the Reticulocytes (MCHr) biomarker in Diagnosis of Iron Deficiency Anemia

Sponsored by: Abbott Diagnostics
C.E. Credits: P.A.C.E. CE Florida CE
  • Professor, Head and Director of the Laboratories at Ruby Hall Hospital, Pune India
      Dr. Nita Munshi is Professor, Head and Director of the Laboratories at Ruby Hall Hospital, Pune India. This is a group of specialty hospitals with 750 beds. She also heads the Steering Committee for Quality Control and is the Chairperson of the Hospital Infection Control Committee.
      Dr. Munshi is an alumna of the Seth G.S. Medical College & KEM Hospital in Mumbai and now has about 34 years of experience in Laboratory Medicine. She is a teacher for post-graduate students in Pathology and also serves as a guide for Ph.D. students at the University of Pune.
      She has also authored chapters in pathology books and has presented papers and posters in both national and international conferences. She is very passionate about Infection Control and hence works closely with Infectious Disease clinicians.
      Dr. Munshi is the President of the Thalassemia Society of Pune and works for the welfare of the children living with thalassemia and their families. She is also a life member of ISHTM, IAPM, ISLH, and HISI.
      Her passions are Hematology and Quality.

    Wednesday, January 29  9:30pm PST
    Thursday, January 30  12:30 am EST, 5:30 am GMT, 6:30 am CET, 11:00 am IST, 2:30 pm JST, 4:30 pm AEDT
    Iron is an essential metal for the body and is required for hemoglobin synthesis in erythrocytes, oxidation reduction reactions & cellular proliferation. Iron deficiency anemia (IDA) is the most common anemia worldwide. It is especially prevalent in women and children in regions where meat intake is low, food is not fortified with iron, and where malaria and other parasitic infections are common. The analysis of Mean Cell Hemoglobin of the reticulocytes (MCHr) by a hematology analyzer can help monitor acute changes in hemoglobin incorporation into the erythron and is more sensitive than indirect chemical methods. Compared with erythrocytes, the shorter lifespan of reticulocytes makes MCHr a better biomarker to reflect short term iron status in patients than hemoglobin values. Since MCHr values can be obtained on a routine CBC, it is an attractive alternative for the diagnosis of IDA especially in countries with high prevalence of the disease.
    Learning Objectives:
    • Review the global impact of iron deficiency anemia (IDA)
    • Describe iron metabolism, absorption, regulation, and storage
    • Review laboratory diagnosis of IDA, including new parameters
    • Share results of IDA study performed on Abbott’s Alinity hq CBC analyzer
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