MAR 12, 2024 10:00 AM PDT

Unveiling Brain Complexity with the MERSCOPE® Platform Using 1000-plex Gene Panels

Sponsored by: Vizgen
Speakers

Event Date & Time
Date: March 12, 2024
Time: 10:00 AM (PST), 1:00 PM (EST), 6:00 PM (CET)
Abstract
In this webinar, we will briefly introduce Vizgen’s Vizgen® MERSCOPE® Platform for spatial transcriptomics. Following this introduction, we will showcase the capabilities of MERSCOPE in deciphering the molecular and cellular features of both mouse and human brain tissue under physiological and pathological conditions. We leveraged the vast gene repertoire of a 960-plex gene panel to achieve unprecedented resolution in neuronal and non-neuronal cell types across disparate mouse brain regions, enabling the molecular and cellular features underpinning various anatomical structures to be uncovered. In addition, by profiling brain samples from normal and AD patient, we could identify cell-type and regions specific molecular changes associated with AD pathogenesis.
 
Learning Objectives
  • Discover high accuracy and detection efficiency of the  MERSCOPE 1000-plex gene panel 
  • Spatial profiling of mouse and human brain with 1000-plex gene panel reveal molecular architecture of the brains
  • Understand how spatial technologies can help uncover the molecular/cellular changes in degenerative disease, such as Alzheimer's disease

 

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