Vertical transmission of viruses from mother to child can occur during pregnancy, labor and delivery, or breastfeeding, and may result in significant morbidity in the neonate. These maternally acquired infections, classified as congenital or perinatal, can lead to a spectrum of clinical outcomes ranging from mild, transient symptoms to severe, long-term complications. This presentation aims to examine the immunological adaptations during pregnancy and provide an overview of viral pathogens that can be transmitted from mother to child.

Learning Objectives:

1. Define and characterize TORCH pathogens and their relevance in the context of vertical transmission.
2. Describe the immunological adaptations that occur across the different stages of pregnancy.
3. Understand the clinical impact of TORCH viral infections on both maternal and neonatal health, and summarize current treatment and management guidelines.