Deep brain Recording and Stimulation of Real World Episodic Memory in Humans

Presented at: Neuroscience 2020
C.E. Credits: P.A.C.E. CE Florida CE
  • Assistant Professor, David Geffen School of Medicine at UCLA
      Nanthia Suthana, Ph.D., is an Assistant Professor of Psychiatry, Psychology, Neurosurgery, and Bioengineering. She completed her B.S. and Ph.D. in Neuroscience and postdoctoral training at UCLA before joining faculty. She uses intracranial recordings and deep brain stimulation in participants with implanted electrodes to understand cognitive function and develop novel therapies. She is a recipient of a NIH Brain Initiative UO1 grant, McKnight Technological Innovations Award in Neuroscience, and the UCLA Keck Junior Faculty Award for her work. She also serves as the Associate Director of the Neuromodulation Division at the Semel Institute for Neuroscience, and the Associate Director of Neuroscience outreach for the Brain Research Institute at UCLA.


    Recent technological advancements in neuroprosthetics allow for wireless recording and stimulation of brain activity in freely moving human participants. At the same time, advancements in virtual and augmented reality (VR/AR) and other wearable technologies are occurring at an unprecedented rate. I will discuss our recently developed platform that allows for wireless and programmable recording and stimulation of deep brain activity in freely moving human participants integrated with wearable sensors (e.g., heart rate, skin conductance, respiration, eye tracking, and scalp EEG) and VR/AR technologies. This research platform allows for a naturalistic and ecologically valid environment for elucidating the neural mechanisms underlying freely moving human behaviors in the real world. As a proof-of-concept, I will present data captured from this platform that provides insight into deep brain oscillatory dynamics that underlie human spatial navigation and episodic memory in real and virtual environments.

    Learning Objectives:

    1. To learn about new opportunities that enable the study of the human brain in naturalistic settings
    2. To gain understanding of the brain mechanisms that support navigation and memory in humans

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