Recent technological advances as well as longitudinal monitoring not only have the potential to improve the treatment of disease (Precision Medicine) but also empower people to stay healthy (Precision Health). We have profiled 109 participants using multiomics technologies (genomics, immunomics, transcriptomics, proteomics, metabolomics, microbiomics and wearables etc) for up to 9.5 years and made 49 major health discoveries. We have also profiled people after an acute bout of exercise and found that thousands of blood molecules change after a short bout of exercise. Lastly, we demonstrate that individuals have distinct aging patterns that can be measured in a period of time that is actionable. We conclude that deep longitudinal profiling can lead to actionable health discoveries and provide relevant information for precision health.

Learning Objectives:

1. What is wrong with healthcare today

2. What kinds of omics and wearables data can be used to best predict disease risk and manage health