Ph.D. Molecular Biology and Biochemistry, University of California, Irvine
Protein biochemist and structural biologist in the field of HIV vaccine design. Duties include design and expression of novel immunogens in mammalian cells, stringent purification protocols for animal immunization studies, and quality control assessment of antigens alone or in presence of adjuvants/buffers using a combination of biolayer interferometry, differential scanning calorimetry, isothermal titration calorimetry, and electron microscopy. Assessment includes samples from GMP-level production. Additional projects involve high-resolution epitope mapping and structural determination of HIV Env trimers using cryoelectron microscopy, with a focus on trimer dynamics.