Name: "shRNA Adeno-associated Virus Serotype 2, pU6-(SNRNP70-shRNA-Seq1)"
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"shRNA Adeno-associated Virus Serotype 2, pU6-(SNRNP70-shRNA-Seq1)" | Creative Biolabs

This product is a SNRNP70-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by SNRNP70 is the component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. Misregulation of this gene has been implicated in the mRNA splicing-major pathway. The expression of SNRNP70-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.