Companies / Creative Biolabs / Recombinant Human Anti-CD3 x Human Anti-CD33 Bispecific Antibody (IgG(L)-scFv)
Creative Biolabs

Recombinant Human Anti-CD3 x Human Anti-CD33 Bispecific Antibody (IgG(L)-scFv) | Creative Biolabs

Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD3 antibody are fused to the C terminus of an anti-CD33 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget T cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.

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ABOUT THE COMPANY

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.