Melanoma is a type of skin cancer that develops in the melanocytes, cells that regulate pigment in the skin. Melanoma research is focusing on developing new approaches to prevent and treat melanoma.
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
DATE: July 20, 2017TIME: 8:00am PT, 11:00am ET, 5:00pm CESTNeurodevelopmental disorders (NDDs) are clinically and etiologically highly heterogeneous and are characterized by a...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
The assessment of pigmented lesions is a difficult area of dermatology and dermatopathology. Melanoma is the leading cause of cancer in woman age 25-29 years, yet it is also a leading c...
Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
This is an exciting time for melanoma treatment, with a half-dozen new drugs approved in just over four years. This influx has brought a new complexity to the field, however, including questi...
Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
While Melanoma is very curable and treatable when detected early, late stage melanoma has had a very poor outcome. In 2013, it is estimated that over 80,000 patients in the US will develop me...
The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
As Chief of Scientific Intelligence at the John Wayne Cancer Institute, Dr. Hoon interacts with external academic, industry, and government agencies to develop innovative translational rese...
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
DATE: July 20, 2017TIME: 8:00am PT, 11:00am ET, 5:00pm CESTNeurodevelopmental disorders (NDDs) are clinically and etiologically highly heterogeneous and are characterized by a...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
The assessment of pigmented lesions is a difficult area of dermatology and dermatopathology. Melanoma is the leading cause of cancer in woman age 25-29 years, yet it is also a leading c...
Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
This is an exciting time for melanoma treatment, with a half-dozen new drugs approved in just over four years. This influx has brought a new complexity to the field, however, including questi...
Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
While Melanoma is very curable and treatable when detected early, late stage melanoma has had a very poor outcome. In 2013, it is estimated that over 80,000 patients in the US will develop me...
The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
As Chief of Scientific Intelligence at the John Wayne Cancer Institute, Dr. Hoon interacts with external academic, industry, and government agencies to develop innovative translational rese...
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