Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
De novo gene synthesis and protein expression are established technologies that can give access to nearly any target DNA or protein sequence, allowing for engineering of biologics. In this p...
There are known health outcome disparities among those with pancreatic neuroendocrine tumors (pNET) of minority race and those living with adverse social determinants of health (SDOH) (rural...
Pancreatic ductal adenocarcinoma (PDAC) is characterized clinically by poor survival and mechanistically by KRAS- and autophagy-dependent growth. We and others previously demonstrated that i...
The 21st Century Cures Act, along with the FDA's Real-World Evidence (RWE) framework, has established a foundation for incorporating real-world data (RWD) into regulatory decision-making...
Solute carriers include numerous uptake transporters that serve as major regulators of drug absorption, disposition, and clearance. Indeed, drug interactions or genetic variation that alter...
Immunotherapy has changed the landscape of oncology, improving survival rates for many patients across a variety of malignancies. Two antibody-based immunotherapies, immune checkpoint inhibi...
Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
To determine efficacy of specific complementary therapies to advance evidence-based, integrative healthcare, the complementary modality should first be introduced to stakeholders to determin...
Cancer neoantigens arise from protein-altering somatic mutations in tumor and rank among the most promising next-generation immuno-oncology agents when used in combination with immune checkp...
Genomic research has long been skewed toward European populations, leading to significant underrepresentation of Non-European groups in both research studies and genomic databases. This bias...
Real-time reverse transcription PCR analysis of RNA expression in normal and diseased states is a fundamental technique used in research workflows. Immortalized and primary cells are often u...
The human antibody repertoire, or reactome, is a vast and dynamic network of antibody-antigen interactions that plays a crucial role in health and disease. Understanding the complexity of th...
The cellular physiology of microbes can vary significantly within a population, even when exposed to identical external conditions. Recent theoretical and experimental studies have shown tha...
Human inborn errors of immunity (IEI) comprise a variety of diseases caused by molecular variants that impair both innate and adaptive immune responses. Patients with IEI often exhibit a sus...
CML is traditionally regarded as a paradigm of precision medicine, under several points of view: 1) it is the first human malignancy whose molecular pathogenesis was unravelled, well before...
The FDA submitted its final rule regarding laboratory diagnostic tests (LDTs) on May 6, 2024. While it allows for 4 years for compliance and it is currently being disputed by various associa...
Heart failure, in the simplest of terms, indicates that a problem with the ventricles is preventing the heart from filling and/or pumping correctly. It is the result of a complex mechanical...
In the rapidly evolving field of oncology, precision medicine stands at the forefront of providing personalized patient care. Our upcoming webinar, "Transforming Oncology Diagnostics: I...
September 19, 2024 | 10 AM EDT, 7AM PDT, 4 PM CEST
The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some m...
Join this year's poster presenters in the Poster Hall during the Poster Discussion, Wednesday , Se ptember 18th, from 1:00pm –2:00pm PDT , to chat live about their posters and late...
This webinar is designed to explore the fundamental characteristics of reverse transcriptases and the essential factors that play a pivotal role in achieving high-quality cDNA synthesis from...
Translational research strives to identify, verify, and validate biomarker candidates that can be used in clinical settings to collectively stratify biology. With the recent introduction of...
The quest to decipher the complex molecular events underpinning cell polarity and organelle segregation during eukaryotic cell division presents a formidable challenge. A predominant focus o...
abstract Learning Objectives Understand how the health disparity affects ordering M-protein testing at the right time. Discuss Analytical considerations of the test panel/methods ordered Ide...
The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
A unique opportunity to deepen understanding of how labs can contribute to antibiotic stewardship efforts by running efficient Procalcitonin testing, yielding significant impacts on patient...
One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...