A study led by investigators from Massachusetts General Hospital and the Perelman School of Medicine at the University of Pennsylvania has identified a possible target for therapies that can treat cocaine addiction. Â The study, which received advance online publication in Molecular Psychiatry, found evidence that changing one amino acid in a subunit of an important receptor protein can change the...... Read More
About 55,000 people die from rabies every year. The dreaded disease causes acute inflammation of the brain, producing psychosis and violent aggression.  The virus, which paralyzes the bodyâs internal organs, is always deadly for those unable to obtain vaccines in time. Tel Aviv University scientists have discovered the exact mechanism this killer virus uses to efficiently enter the central nervous...... Read More
BGN Technologies, the technology transfer company of Ben-Gurion University of the Negev (BGU), EMC Corporation and Jerusalem Venture Partners recently announced the CyberSpark Industry Initiative, which will serve as a coordinating body for joint cyber industry activities with government agencies, the Israel Defense Force (IDF) and academia. The innovative public/private cyber center established in...... Read More
With drug companies investing huge amounts of time and money to produce viable products, it is not surprising that they look for drug candidates that will provide a return on the investment. Whereas rare diseases may not have been the way to go before, there are indications that the trend may be changing in some sectors. A case for developing drugs for rare, orphan diseases can be found in the most...... Read More
After multiple months of waiting for final permits, the Oakland Zoo has acquired the necessary state and federal permits to help save the Mountain Yellow-Legged frog, a highly endangered amphibian. This frog species, which once hopped throughout California’s upper elevations, has dropped significantly in numbers, more than ninety percent in the past decade, due in part to chytrid, a skin fungus that...... Read More
While not normally thought of as a dodgy character, the sea trout, a distant cousin of the Norwegian Salmon has a lot of secrets. Researcher Jan G. Davidson and his graduate students are on the case and trying to decipher the development and habits of the sea trout and in the process hopefully discover why there has been a 60% reduction in the numbers of sea trout in Norway. Similar to their salmon...... Read More
Researchers at the Salk Institute, La Jolla, Calif, have repaired injured hearts in mice by reviving long-inactive molecular machinery in the animalsâ cells, which may lead to new therapies for human heart ailments. The mice exhibited dramatic improvement in heart regeneration and healing after the researchers blocked four molecules believed to suppress these programs for regenerating organs. The...... Read More
Autoimmune diseases that affect millions of peopleâincluding type 1 diabetes, multiple sclerosis, rheumatoid arthritis, and asthmaâwhich mystifyingly cause the immune system to damage tissues in our bodies, may harbor a complex genetic component, a new study finds. This discovery could prompt better diagnosis and someday, better treatment options. A team of scientists from UC San Francisco,...... Read More
Given my sisterâs history, I often wished she had Down syndrome. Iâm sure that sounds odd, but when I was a kid, not to me. Jill was found to have Cornelia de Lange Syndrome (CdLS), a genetic disorder that bestows odd facial features and a small head, small stature, profuse body hair, heart problems, difficulty with eating, and often, interpersonal challenges and delayed development. Jillâs...... Read More
A new wrinkle in federal funding for disputed gain-of-function studies (GOF) in which pathogens are modified to make them lethal or easier to transmitâthe White House is putting funding on hold while experts craft a government-wide policy for evaluating the risks. The funding âpause,â says a White House blog (from the Office of Science and Technology Policy), would pertain to new studiesthat...... Read More