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Amerigo Scientific

"[Cys(Et)2&7]-α-CGRP, human" | Amerigo Scientific

[Cys(Et)2&7]-α-CGRP, human

MW: 3848

H-Ala-Cys(Et)-Asp-Thr-Ala-Thr-Cys(Et)-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2

This peptide is a potent CGRP-2 receptor agonist. The CGRP alpha analogue exhibits a high potency to inhibit the rat vas deferens twitch response, but induces only a slight inotropic effect in guinea pig atrium even at very high concentrations. It also competes with labelled hCGRP alpha with high affinity

for binding sites in rat brain homogenates. These results suggest that this analogue will be valuable in assessing the functional relevance of CGRP-2 receptors.

Dumont et al. (1997) Can. J. Physiol.Pharmacol. 75, 671-676.

500µg

1mg

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ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
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