ViroMag R/L Transduction Reagent is a magnetic nanoparticles formulation optimized for Retroviruses and Lentiviruses. Based on the Magnetofection™technology, this reagent allows concentrating the complete applied dose of Retro/Lentiviral particles onto cells within minutes, inducing a significant improvement of virus infectivity with extremely low vector doses. Due to its specific properties, ViroMag R/L is ideal to infect non permissive cells. This reagent demonstrates an exceptionally high efficiency to promote, control and assist viral transductions in a so that no molecular biology processes or biochemical modifications are required.

Increase transduction efficiency

Accelerate the transduction process

Efficient for hard-to-infect and non-permissive cells

Concentrate the viral dose onto the cells

Suitable for all type of Retro/Lentivirus

Synchronise cells adsorption/infection without modifications of the viruses/

Use of ViroMag R/L to knock down a gene by CRISPR/Cas9-guided genome editing with Lentivirus in THP-1 cells Safronova A et al, Nature Immuno. 2018

The magnetofection beads have been a game-changer for the transduction efficiency of our lentiviruses. We are using very hard to transduce B-lymphoblastomas that grow in suspension and viral concentration using filtering in conjunction with ViroMag R/L has brought our efficiency up from about 2% to 70-80%.High transduction efficiency on mammary epithelial organoids in suspension

Erna Magnúsdóttir - University of Iceland/

ViroMag R/L transduction reagent:

Sizes :

100 µL 30-500 transductions in 96-well plate

200 µL 60-1,000 transductions in 96 well plate

1 mL 300-5,000 transductions in 96-well plate

#KC30700: ViroMag R/L Starting Kit with Super Magnetic plate + 200µL of ViroMag R/L