Reviews
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
iCrea™ ADCC CD16a (158V) (Luc) Reporter Cell Line, Human Jurkat Cells | Creative Biolabs
Creative Biolabs developed and successfully established human CD16a (158V) (Luc) reporter cell line. The cells have been engineered to express not only the NFAT response elements that drive the luciferase expression system, but also express full length human CD16a receptor mutated to a Valine (V) at amino acid 158 that can be used to assess the ADCC activity of antibodies. CD16a (158V) exhibits a higher affinity for IgG1 and IgG3 isotypes compared to CD16a-158F.
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