Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CCR3 antibody are fused to the C terminus of an anti-CD300 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.