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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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Human immunity is an incredibly complex system that have to be very carefully regulated by the body. We need our immune ...Written By: Carmen LeitchDEC 07, 2023Immunology
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Genetic mutations that happen in a gene called apolipoprotein E (APOE) have long been known to have a significant impact ...Written By: Carmen LeitchNOV 06, 2023Genetics & Genomics
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Mobile genetic elements (MGEs) are a kind of mobile genetic material; in nature, they can change places in within the ge ...Written By: Carmen Leitch
FEB 27, 2024
Cell & Molecular Biology
Trillions of microbes live in the human gastrointestinal tract, and this community of microbes known as the gut microbio
...
Written By:
Carmen Leitch
FEB 21, 2024
Genetics & Genomics
The increase of the length of some small portions of DNA, or microsatellite repeat expansions, has been linked to a numb
...
Written By:
Carmen Leitch
FEB 15, 2024
Immunology
Scientists have dedicated their lives to finding a cure for cancer. America became a science hub for cancer research, pa
...
Written By:
Brian G. Morreale
FEB 12, 2024
Genetics & Genomics
In the genome, genes that code for protein are often divided into sections called exons, which are separated by spacers
...
Written By:
Carmen Leitch
FEB 07, 2024
Genetics & Genomics
In many amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients, symptoms of autoimmune inflammat
...
Written By:
Carmen Leitch
FEB 06, 2024
Clinical & Molecular DX
The detection of rare variants in the genome can take time and cost a lot of money. In recent years, scientists and clin
...
Written By:
Carmen Leitch
FEB 06, 2024
Genetics & Genomics
The CRISPR gene editing tool was developed about a decade ago, and since then it has transformed research in the life sc
...
Written By:
Carmen Leitch
JAN 30, 2024
Genetics & Genomics
A single, small mutation can have an impact on other genes that one researcher likens to a "butterfly effect."
Written By:
Carmen Leitch
JAN 30, 2024
Cell & Molecular Biology
Introduction Clinical medicine aims to develop novel treatments to fight disease and as a result, must constantly
...
JAN 29, 2024
Microbiology
Our immune systems can often eliminate bacterial infections, but sometimes those bacteria are very tough and persistent,
...
Written By:
Carmen Leitch
JAN 17, 2024
Genetics & Genomics
DNA molecules are very lengthy, and most cells in the body have to fit the entire genome into the nucleus. To do so, the
...
Written By:
Carmen Leitch
JAN 16, 2024
Cell & Molecular Biology
The various identities of cells, whether they are in the brain, heart, kidney, or any other tissue, are defined by the g
...
Written By:
Carmen Leitch
JAN 10, 2024
Genetics & Genomics
Zellweger Spectrum Disorder (ZSD) is a term for a rare group of neurodegenerative disorders that are caused by mutations
...
Written By:
Carmen Leitch
JAN 02, 2024
Genetics & Genomics
Scientists have identified a genetic mutation in a gene called SHLP2, which encodes for a microprotein in mitochondria,
...
Written By:
Carmen Leitch
DEC 29, 2023
Genetics & Genomics
Almost nine percent of American children will be diagnosed with ADHD at some point, according to the Centers for Disease
...
Written By:
Carmen Leitch
DEC 19, 2023
Drug Discovery & Development
The potential of IL-1beta inhibitors to mitigate inflammation and improve clinical outcomes in patients with CMML and ot
...
Written By:
Amielle Moreno
DEC 14, 2023
Immunology
A gene editing tool using a system known as CRISPR-Cas9 has recently been approved by the U.S. Food and Drug Administrat
...
Written By:
Brian G. Morreale
DEC 13, 2023
Genetics & Genomics
Human immunity is an incredibly complex system that have to be very carefully regulated by the body. We need our immune
...
Written By:
Carmen Leitch
DEC 07, 2023
Immunology
Breast cancer is one of the most common cancers diagnosed in women. According to the American Cancer Society, it is
...
Written By:
Brian G. Morreale
NOV 22, 2023
Immunology
Individuals with genetic diseases have an increased chance of lower quality of life. However, a new technology has been
...
Written By:
Brian G. Morreale
NOV 16, 2023
Immunology
Cancer is very difficult to treat due to various components that therapies must address to effectively kill or lyse tumo
...
Written By:
Brian G. Morreale
NOV 14, 2023
Genetics & Genomics
Genetic mutations that happen in a gene called apolipoprotein E (APOE) have long been known to have a significant impact
...
Written By:
Carmen Leitch
NOV 06, 2023
Genetics & Genomics
How did cats evolve into so many different species, like tigers, panthers, and domestic cats? A new study has explored c
...
Written By:
Carmen Leitch
NOV 03, 2023
Genetics & Genomics
Mobile genetic elements (MGEs) are a kind of mobile genetic material; in nature, they can change places in within the ge
...
Written By:
Carmen Leitch