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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
What's Popular in Gene mutations
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Smoking can cause lung cancer. But not all smokers get lung cancer, and about 25% of all lung cancer patients have never
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Carmen Leitch
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Researchers have developed a gene editing strategy that can repair the genetic problems that lead to Huntington's diseas
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Carmen Leitch
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JAN 16, 2024 | 8:00 AM
The clinical interpretation of genetic testing results remains one of the most significant hurdles in effectively applying genomics in modern medicine. Errors in variant interpretation, whet...DEC 07, 2023 | 8:00 AM
As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...NOV 16, 2023 | 10:00 AM
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Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
JUL 20, 2023 | 8:00 AM
Single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing, scATAC-seq) is a relatively new and powerful technique that allows researchers to identify open chromatin r...
JAN 16, 2024 | 8:00 AM
The clinical interpretation of genetic testing results remains one of the most significant hurdles in effectively applying genomics in modern medicine. Errors in variant interpretation, whet...
DEC 07, 2023 | 8:00 AM
As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
NOV 16, 2023 | 10:00 AM
Across various stages of the clinical oncology workflow, from panel design to genomic testing and molecular tumor boards, the identification and validation of actionable genomic alterations...
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Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
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Our understanding of cancer mechanisms, genetics and complexities continues to expand rapidly. Without a streamlined, standardized and easy to understand organizational system to keep track...
APR 19, 2023 | 10:00 AM
Date: April 18, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Whilst a decade ago the prognosis of lung cancer patients has been very disappointing, nowadays a substantial evolutio...
APR 11, 2023 | 8:00 AM
Date: April 11, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Duchenne muscular dystrophy is caused by mutations in the dystrophin encoding DMD gene that disrupt the reading frame. M...
MAR 30, 2023 | 12:05 PM
In this study, we evaluated the concordance of targeted sequencing results between paired ctDNA and tumor samples from early breast cancers scheduled for curative surgery with or without adj...
Speaker:
Dr. Chi-Cheng Huang, PhD
Presented at: OncomineWorld 2023: A Virtual NGS Education Meeting
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OCT 22, 2024 | 10:00 AM PDT
For the Love of Digital PCR 2024 virtual event Welcome to For the Love of Digital PCR 2024 – an immersive multi-day virtual event dedicated to exploring the remarkable capabilities of...MAR 20, 2024 | 8:30 PM PDT
The premier event in NGS education is now available on demand. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each y...JUL 26, 2023 | 8:00 AM PDT
GenScript is delighted to announce its 3rd Annual Virtual Summit on Gene and Cell Engineering. This gathering will feature leaders in the life sciences from academia, pharma, and biotech, le...MAR 30, 2023 | 12:00 AM PDT
Don’t miss the premier event in NGS education. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each year to adv...OCT 19, 2022 | 5:30 AM PDT
Labroots announces the 2022 Coronavirus Virtual Event Series. A novel coronavirus emerged in China in 2019; it has since been dubbed COVID-19....
OCT 22, 2024
| 10:00 AM PDT
For the Love of Digital PCR 2024 virtual event Welcome to For the Love of Digital PCR 2024 – an immersive multi-day virtual event dedicated to exploring the remarkable capabilities of...
MAR 20, 2024
| 8:30 PM PDT
The premier event in NGS education is now available on demand. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each y...
JUL 26, 2023
| 8:00 AM PDT
GenScript is delighted to announce its 3rd Annual Virtual Summit on Gene and Cell Engineering. This gathering will feature leaders in the life sciences from academia, pharma, and biotech, le...
MAR 30, 2023
| 12:00 AM PDT
Don’t miss the premier event in NGS education. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each year to adv...
OCT 19, 2022
| 5:30 AM PDT
Labroots announces the 2022 Coronavirus Virtual Event Series. A novel coronavirus emerged in China in 2019; it has since been dubbed COVID-19....
SEP 06, 2022
| 6:00 AM PDT
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JUL 28, 2022
| 8:00 AM PDT
GenScript is delighted to announce its 2nd Annual Virtual Summit on Gene and Cell Engineering. This gathering will feature leaders in the life sciences from academia, pharma, and biotech, lev...
JUN 22, 2022
| 3:00 AM PDT
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MAY 18, 2022
| 5:30 AM PDT
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