Multiplexing: is a method by which multiple analog or digital signals are combined into one signal over a shared medium. The aim is to share a scarce resource. For example, in telecommunications, several telephone calls may be carried using one wire.
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Patient-derived tumoroids, also known as cancer organoids, hold potential as cost-effective models for cancer immunotherapy research. Patient-derived tumor models, which mimic the tumor micr...
Preliminary data indicate the presence of inflammatory derangements in AML, necessitating a comprehensive examination of inflammatory effector cytokines involved in AML pathogenesis and ther...
Alamar NULISAseq is a novel commercial platform for highly multiplexed analysis of soluble proteins using a modified proximity ligation assay. We compared Luminex, Olink, and NULISAseq platf...
Success stories in the field of cell therapies are making headlines on a daily basis. These achievements involve complex manufacturing processes in which cytokines play a key role. Choosing...
Recent developments in mass spectrometry-based single-cell proteomics (SCP) have resulted in dramatically improved sensitivity, yet the relatively low measurement throughput remains a limita...
Quantitative mass spectrometry-based proteomic experiments are designed to answer increasingly complex questions. For example, we may want to characterize changes in protein abundance in bio...
Targeted proteomics enables hypothesis-driven research by measuring the expression of protein cohorts related by function or disease in systems biology. Here, I highlight a strategy, termed...
In recent years, significant progress has been made in tissue-based technology, opening up unparalleled opportunities for identifying disease process biomarkers and gaining invaluable insigh...
The multiplexing capability of tandem mass tags (TMT) has driven quantitative proteomic experimental designs towards larger numbers of samples. In order to efficiently process hundreds to th...