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Orthotopic Models
Orthotopic models are generated by inoculating tumor cell lines into the anatomically corresponding tissue in an animal model, for example, seeding a breast cancer cell line into the mammary fat pad of a mouse. This type of model is beneficial to translational research as the tumor can be evaluated in a highly relevant environment and it closely mimics human disease.
JUN 02, 2021 | 12:00 AM
Rhabdomyosarcoma (RMS) is a soft tissue cancer commonly arising in muscle and is the most common soft tissue cancer in children. Patients with metastatic RMS have a poor prognosis that has n...