MAY 30, 2019 11:01 AM PDT

Uterine Cancer Rises, Especially Among Black Women

WRITTEN BY: Julia Travers

A recent study from the National Cancer Institute (NCI) found uterine cancer rates among all women rose about 1 percent per year between 2003 and 2015. It’s important to note that this is a hysterectomy-corrected finding, meaning that it took hysterectomy prevalence into account, because women with hysterectomies do not develop this disease. The authors also found that aggressive, nonendometrioid cancers are increasing for all women, and that significant racial disparities exist in uterine cancer rates. Black women are experiencing documented increases in uterine cancer above other groups of women, as well as lower rates of survival.

Rising Uterine Cancer Rates

Relying on population data from NCI’s Surveillance, Epidemiology and End Results (SEER) database, the researchers found uterine cancer rates rose between 2000 and 2015 and, overall, it increased more rapidly among women who were not white. The study also looked at data on endometrioid and nonendometrioid subtypes of uterine cancer. Nonendometrioid cancers are rarer and generally have lower survival rates.

Incidence rates of endometrioid cancers were stable in white women and increased in women of other groups. But rates of the less common, aggressive, nonendometrioid subtypes have been increasing “dramatically” in all groups and especially among black women, who experienced a rate of 25.9 per 100,000 women. The rate for white women was 11.4 per 100,000; for Hispanic women, 10.1; and for Asian/Pacific Islander women, 7.5.

Also, the 5-year survival rate was lower among all women with nonendometrioid subtypes, and black women had the lowest survival rates throughout each of the categories.

graph showing rates of aggressive uterine cancer subtypes between 2000 and 2015, credit: NCI

Racial Disparities in Cancer

“All of these trends—the rates of uterine cancer among black women exceeding those of white women, the higher incidence rates of nonendometrioid subtypes among black women, and the lower survival rates of black women for all uterine cancer—are very concerning,” Megan Clarke, Ph.D., lead author of the study and postdoctoral fellow in NCI’s Division of Cancer Epidemiology and Genetics, said.

Diagram of uterus, credit: NCI

And, these are not isolated findings. As we covered in 2018, a racial imbalance continues to be evident in regard to lower health care quality and higher cancer risk for Blacks, Hispanics and Latinos, along with individuals in poverty. Cancer incidence and mortality are generally highest among non‐Hispanic Blacks, the American Cancer Society (ACS) reported once again in 2019. “Cancer occurrence and outcomes vary considerably between racial and ethnic groups, largely because of inequalities in wealth that lead to differences in risk factor exposures and barriers to high‐quality cancer prevention, early detection and treatment.”

“We need to continue research to further understand these racial differences and disparities, in order to help us better predict risk and work toward prevention,” Dr. Clarke said of her study’s findings.

In 2019, an estimated 61,880 women in the U.S. will be diagnosed with uterine cancer. The ACS predicts that 12,160 deaths from the various forms of uterine cancer will occur this year. It is the fourth most common cancer for women in the U.S. and the sixth most common cause of cancer death for this population.

Sources: National Cancer Institute, American Cancer Society, American Society of Clinical Oncology

About the Author
  • Julia Travers is a writer, artist and teacher. She frequently covers science, tech, conservation and the arts. She enjoys solutions journalism. Find more of her work at jtravers.journoportfolio.com.
You May Also Like
OCT 08, 2020
Cancer
Oral cancer pain levels indicate metastasis
OCT 08, 2020
Oral cancer pain levels indicate metastasis
A new study from NYU College of Dentistry researchers provides insight as to why patients with metastatic oral cancer ex ...
OCT 12, 2020
Cancer
Urine analysis is better at detecting bladder cancer than urine cytology
OCT 12, 2020
Urine analysis is better at detecting bladder cancer than urine cytology
In a study published recently in the American Association for Cancer Research journal Clinical Cancer Research, scientis ...
OCT 19, 2020
Cancer
Using qPCR to Diagnose Common Cancer Mutations in Lung Cancer
OCT 19, 2020
Using qPCR to Diagnose Common Cancer Mutations in Lung Cancer
Cancer is a disease characterized by DNA mutations. These mutations, while sometimes small, can cause havoc in a cell&rs ...
OCT 18, 2020
Cancer
Virus-mimicking drug attacks melanoma tumors
OCT 18, 2020
Virus-mimicking drug attacks melanoma tumors
Research published recently in the journal Science Translational Medicine from scientists at the UCLA Jonsson Compr ...
OCT 22, 2020
Cancer
Cancer cells don't like crowded spaces
OCT 22, 2020
Cancer cells don't like crowded spaces
Researchers collaborating from St. Anna Children's Cancer Research Institute Vienna, King's College London, Inst ...
NOV 22, 2020
Cancer
Unmet social needs influence patient breast health care
NOV 22, 2020
Unmet social needs influence patient breast health care
New research to be presented at the annual meeting of the Radiological Society of North America will report on the breas ...
Loading Comments...