MAY 28, 2016 6:53 AM PDT

First Simultaneous Skull-Scalp, Kidney, and Pancreas Transplant

WRITTEN BY: Xuan Pham
In a medical first, doctors from Houston, Texas reported a simultaneous scalp, skull, kidney, and pancreas transplant from one donor to a recipient. The drastic, never-been-done-before procedure allowed a patient to reclaim better health outcomes that would otherwise not be possible. Additionally, doctors hope this medical case will open the door for more combined transplants in the future.
 
Texas man gets new skull-scalp transplant along with 2 organs
The recipient of this landmark procedure is a 55-year-old man who has type 1 diabetes. The patient underwent kidney and pancreas transplantation over 20 years ago, but the kidney organ is now failing. In 2005, the patient developed an aggressive cancer on his scalp that was successfully treated, but left him with a large, non-healing scalp wound that was prone to severe infections.
 
His team of doctors weighed their options to treat the multi-organ complications in this patient. They concluded that a scalp and skull transplant could be performed at the same time the kidney and pancreas transplant was taking place, provided the organs came from the same donor.
 
The scalp and skull transplantation is different than the solid organ transplant in that it involves connecting multiple types of tissues, like skin, muscle, blood vessels, nerves, and bone. Known as vascularized composite allotransplantation, or VCA, the procedure requires a lifelong need for immunosuppressive therapy to prevent rejection. Previous face and hand transplants proved the success of VCA, but doctors have not attempted to combine VCA with other organ transplants at the same time.
 
In the case of this diabetic patient who was already taking immunosuppressive medications, the scalp/skull VCA combined with the double organ transplant seemed a to be a viable measure to both the doctors and the patient.
 
It took 18 months to find a suitable deceased donor who matched the patient’s immune type, head size, skin color, and hair pattern. Then it took 20 surgeons 15 hours in the operating room to make the transplant a success.
 
Doctors noted the transplants received adequate blood supply and seemed to function normally. The patient experienced a brief episode of rejection with the scalp/skull transplant that was successfully thwarted. A year later, the patient is reported to be in good health, benefiting from his transplanted organs and the corrected defect on his skull.
 
 
"Hopefully, this case and others like it will help to widen the narrow indications for this fascinating new field of reconstructive surgery," said Jesse Creed Selber at the University of Texas M.D. Anderson Cancer Center, first author of the report.

Additional source: EurekAlert!, Plastics and Reconstructive Surgery Journal
About the Author
I am a human geneticist, passionate about telling stories to make science more engaging and approachable. Find more of my writing at the Hopkins BioMedical Odyssey blog and at TheGeneTwist.com.
You May Also Like
JUL 30, 2022
Health & Medicine
Large-Scale Study Suggests Link Between Temporary Menstrual Changes and Covid-19 Vaccine
JUL 30, 2022
Large-Scale Study Suggests Link Between Temporary Menstrual Changes and Covid-19 Vaccine
The most comprehensive analysis of menstrual changes following a Covid-19 vaccination has revealed that its recipients e ...
JUL 31, 2022
Technology
Sticker Worn on the Skin Produces Continuous Ultrasound Images
JUL 31, 2022
Sticker Worn on the Skin Produces Continuous Ultrasound Images
Ultrasound technology has been a revolutionary tool used to diagnose conditions and get a better understanding of what&r ...
AUG 04, 2022
Health & Medicine
Researchers Investigate Memory Strategy to Slow Cognitive Decline
AUG 04, 2022
Researchers Investigate Memory Strategy to Slow Cognitive Decline
A team of researchers from University of Michigan and Penn State College of Medicine compared two mnemonic strategies fo ...
AUG 19, 2022
Coronavirus
Most Omicron-Infected People Are Unaware of Their Infection
AUG 19, 2022
Most Omicron-Infected People Are Unaware of Their Infection
Since the start of the pandemic, researchers and clinicians have warned that not everyone who is infected with SARS-CoV- ...
SEP 06, 2022
Clinical & Molecular DX
Low Testosterone May Increase Risk of COVID-19 Hospitalization For Men
SEP 06, 2022
Low Testosterone May Increase Risk of COVID-19 Hospitalization For Men
Low testosterone in men, also referred to as male hypogonadism, can impact health and development in a multitude of ways ...
SEP 28, 2022
Health & Medicine
Drinking Tea Shown to Reduce Diabetes
SEP 28, 2022
Drinking Tea Shown to Reduce Diabetes
Researchers have discovered that drinking at least four cups of tea per day is associated with a 17% lower risk of type ...
Loading Comments...