FEB 20, 2016 1:10 PM PST

Chronic Exposure to Air Pollution Increases Risk of Obesity

WRITTEN BY: Julianne Chiaet
Smog over Beijing's Forbidden City
Air pollution can have devastating effects on a person’s health. According to the World Health Organization, being exposed to air pollution increases a person’s risk of heart disease, lung cancer, and respiratory diseases. Now, Duke University researchers have found that breathing in the polluted air could also increase one’s risk of obesity.

Laboratory rats that were exposed to Beijing’s highly polluted air gained weight and developed cardiorespiratory and metabolic dysfunction. The rats developed the symptoms between three to eight weeks. The symptoms were more pronounced the longer the rats breathed in the polluted air.
To study the effect of the polluted air on the animal models, the researchers placed pregnant rats and their offspring in two chambers. One of the chambers was exposed to outdoor Beijing air. The other chamber contained an air filter that removed most of the air pollutants.

After 19 days, the lungs and livers of the pregnant rats living in Beijing air had become heavier and their tissue was inflamed. Compared to the rats living in filtered air, these rats had 50 percent higher LDL cholesterol, 46 percent higher triglycerides, and 97 percent higher total cholesterol. In addition, they had a higher insulin resistance level than the clean-air rat group and were therefore at a higher risk of developing type-2 diabetes.

The two rat groups ate the same diet, but the pregnant pollution exposed rats were significantly heavier at the end of their pregnancy than the clean-air rats. The results suggest that breathing in air pollution results in metabolic dysfunction, which is a precursor to obesity.

The offspring of the mice displayed similar results. At eight weeks old, the polluted air male rats were 18 percent heavier than their clean air counterparts. The polluted air female rats were 10 percent heavier.

"Since chronic inflammation is recognized as a factor contributing to obesity and since metabolic diseases such as diabetes and obesity are closely related, our findings provide clear evidence that chronic exposure to air pollution increases the risk [of] developing obesity," said Junfeng "Jim" Zhang, a professor of global and environmental health at Duke University and a senior author of the paper.

"If translated and verified in humans, these findings will support the urgent need to reduce air pollution, given the growing burden of obesity in today's highly polluted world," Zhang said.

The study was published on February 18, 2016, in the FASEB journal
About the Author
  • Julianne (@JuliChiaet) covers health and medicine for LabRoots. Her work has been published in The Daily Beast, Scientific American, and MailOnline. While primarily a science journalist, she has also covered culture and Japanese organized crime. She is the New York Board Representative for the Asian American Journalists Association (AAJA). • To read more of her writing, or to send her a message, go to Jchiaet.com
You May Also Like
JUN 22, 2020
JUN 22, 2020
A Human Gut Microbe Can Help Maintain Healthy Cholesterol Levels
The world is full of microorganisms, and our bodies are one of the many places they have colonized. These gut microbes c ...
JUL 02, 2020
JUL 02, 2020
Managing the Mitochondria After a Heart Attack
Heart attacks are an unfortunately common occurrence across the country. One of the biggest consequences of a heart atta ...
JUL 03, 2020
JUL 03, 2020
Using Machine Learning to Further Classify Triple-Negative Breast Cancer
One of the challenges of facing cancer researchers is coming up with a clearly defined classification system. Cancer is ...
JUL 02, 2020
JUL 02, 2020
Light to Moderate Drinking May Prevent Cognitive Decline in Older Adults
A study from the University of Georgia has found that light to moderate drinking may preserve brain function in older ag ...
JUL 05, 2020
Drug Discovery & Development
JUL 05, 2020
New Drug May Reduce Inflammation from COVID-19
Scientists from the University of Toronto have identified a new drug candidate that may reduce all kinds of inflammation ...
JUL 08, 2020
Health & Medicine
JUL 08, 2020
The Myths About CBD and Coronavirus
Research collected over the last 20 years suggests that cannabidiol – the primary cannabinoid in CBD oil – h ...
Loading Comments...