MAR 25, 2015 6:27 AM PDT

Thomson Reuters Names Most Promising Drugs of 2015

WRITTEN BY: Ilene Schneider
The Thomson Reuters annual forecast found a significant increase in the number of blockbusters set to enter this year's market. The Intellectual Property and Science Business of Thomson Reuters Annual Forecast found a significant increase in the number of blockbusters set to enter this year's market.

The study revealed a significant increase in the number of expected blockbusters from three drugs in 2014 to eleven in 2015. Three of the new drugs are expected to reach over $3 billion in sales by 2019. Thomson Reuters analysts utilized Cortellis™ Competitive Intelligence, its source for drug pipeline, deals, patents, and company content, to forecast the new-to-market drugs expected to lead the pack in sales and potentially emerge as blockbusters (earning $ 1 billion+) by 2019.

At the beginning of 2014, Thomson Reuters Cortellis Competitive Intelligence named three drugs expected to enter the market that year and achieve sales of over $1 billion within five years. All are still forecast to be $1 billion-plus blockbusters, according to the 2015 report. They are Gilead Sciences' oral drug Sovaldi (sofosbuvir) for hepatitis C virus (HCV) infection, GlaxoSmithKline/Theravance's Anoro Ellipta (umeclidinium plus vilanterol) for chronic obstructive pulmonary disease (COPD) and Gilead was Zydelig (idelalisib) for chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin's lymphomas such as follicular B-cell non-Hodgkin lymphoma (FL) and small lymphocytic lymphoma (SLL).

In its 2015 report Thomson Reuters predicts that three drugs will exceed $3 billion in sales by 2019: Bristol-Myers Squibb's (BMS) melanoma drug Opdivo (nivolumab); Regeneron Pharmaceuticals and Sanofi's Praluent (alirocumab) for hypercholesterolemia and Novartis' LCZ-696 (sacubitril and valsartan) for chronic heart failure. Thomson Reuters also predicts other "blockbuster" drug entrants: Pfizer's Ibrance (palbociclib) for breast cancer; Vertex Pharmaceutical's lumacaftor plus ivacaftor for cystic fibrosis; AbbVie's Viekira Pak (veruprevir, ritonavir, ombitasvir and dasabuvir) for HCV; Amgen and Astellas Pharma's evolocumab for hypercholesterolemia/hyperlipidemia; Merck & Co.'s Gardasil 9 vaccine against human papillomavirus (HPV) infection; Otsuka Pharmaceutical and Lundbeck's brexpiprazole for schizophrenia and depression; Sanofi's Toujeo (new-formulation insulin glargine) for diabetes; and Novartis' Cosentyx (secukinumab) for psoriasis and psoriatic arthritis.

The report goes on to say, "Key trends to watch in 2015 are the rise of immuno-oncology approaches for treating cancer, the race to be the next big cholesterol drug, the entry of a first-in-class heart failure drug, and the entry of more convenient all-oral regimes for HCV. Opdivo versus Keytruda is the race to watch in the immuno-oncology space, while Praluent and evolocumab battle it out in the cholesterol field, LCZ-696 aims to make its mark for heart failure, and Gilead, AbbVie and Merck compete to win space in the HCV market." It concludes that far more blockbusters will enter the market this year than in 2014.
About the Author
  • Ilene Schneider is the owner of Schneider the Writer, a firm that provides communications for health care, high technology and service enterprises. Her specialties include public relations, media relations, advertising, journalistic writing, editing, grant writing and corporate creativity consulting services. Prior to starting her own business in 1985, Ilene was editor of the Cleveland edition of TV Guide, associate editor of School Product News (Penton Publishing) and senior public relations representative at Beckman Instruments, Inc. She was profiled in a book, How to Open and Operate a Home-Based Writing Business and listed in Who's Who of American Women, Who's Who in Advertising and Who's Who in Media and Communications. She was the recipient of the Women in Communications, Inc. Clarion Award in advertising. A graduate of the University of Pennsylvania, Ilene and her family have lived in Irvine, California, since 1978.
You May Also Like
AUG 06, 2020
Immunology
Resetting the Body's Danger Sensor
AUG 06, 2020
Resetting the Body's Danger Sensor
The human body has a sophisticated danger-sensing mechanism that alerts the immune system when something is not right. T ...
AUG 05, 2020
Immunology
Intercepting Cancer Cells Before They Can Dodge the Immune System
AUG 05, 2020
Intercepting Cancer Cells Before They Can Dodge the Immune System
The battle that naturally occurs between the body’s immune system and cancerous cells is one that scientists have ...
OCT 06, 2020
Drug Discovery & Development
New Immunotherapy Drug Effective Against Lung Cancer
OCT 06, 2020
New Immunotherapy Drug Effective Against Lung Cancer
A new study has confirmed that Tecentriq, an immunotherapy drug, improves survival rates among those with newly diagnose ...
OCT 12, 2020
Genetics & Genomics
The Malaria Parasite Can Change Host Cell Genetics
OCT 12, 2020
The Malaria Parasite Can Change Host Cell Genetics
Mosquitoes can transmit the malaria-causing Plasmodium parasite to humans. Malaria was estimated to have caused the deat ...
NOV 09, 2020
Drug Discovery & Development
New Immunotherapy Shows Promise for MS
NOV 09, 2020
New Immunotherapy Shows Promise for MS
Researchers from Thomas Jefferson University in Philadelphia are studying an immunotherapy that has shown early pro ...
NOV 17, 2020
Immunology
6 Injections a Year Prevent HIV Infections
NOV 17, 2020
6 Injections a Year Prevent HIV Infections
Last year, around 1.7 million people became infected with HIV, with around half of these being women. Encouraging result ...
Loading Comments...