MAR 25, 2015 06:27 AM PDT

Thomson Reuters Names Most Promising Drugs of 2015

The Thomson Reuters annual forecast found a significant increase in the number of blockbusters set to enter this year's market. The Intellectual Property and Science Business of Thomson Reuters Annual Forecast found a significant increase in the number of blockbusters set to enter this year's market.

The study revealed a significant increase in the number of expected blockbusters from three drugs in 2014 to eleven in 2015. Three of the new drugs are expected to reach over $3 billion in sales by 2019. Thomson Reuters analysts utilized Cortellis™ Competitive Intelligence, its source for drug pipeline, deals, patents, and company content, to forecast the new-to-market drugs expected to lead the pack in sales and potentially emerge as blockbusters (earning $ 1 billion+) by 2019.

At the beginning of 2014, Thomson Reuters Cortellis Competitive Intelligence named three drugs expected to enter the market that year and achieve sales of over $1 billion within five years. All are still forecast to be $1 billion-plus blockbusters, according to the 2015 report. They are Gilead Sciences' oral drug Sovaldi (sofosbuvir) for hepatitis C virus (HCV) infection, GlaxoSmithKline/Theravance's Anoro Ellipta (umeclidinium plus vilanterol) for chronic obstructive pulmonary disease (COPD) and Gilead was Zydelig (idelalisib) for chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin's lymphomas such as follicular B-cell non-Hodgkin lymphoma (FL) and small lymphocytic lymphoma (SLL).

In its 2015 report Thomson Reuters predicts that three drugs will exceed $3 billion in sales by 2019: Bristol-Myers Squibb's (BMS) melanoma drug Opdivo (nivolumab); Regeneron Pharmaceuticals and Sanofi's Praluent (alirocumab) for hypercholesterolemia and Novartis' LCZ-696 (sacubitril and valsartan) for chronic heart failure. Thomson Reuters also predicts other "blockbuster" drug entrants: Pfizer's Ibrance (palbociclib) for breast cancer; Vertex Pharmaceutical's lumacaftor plus ivacaftor for cystic fibrosis; AbbVie's Viekira Pak (veruprevir, ritonavir, ombitasvir and dasabuvir) for HCV; Amgen and Astellas Pharma's evolocumab for hypercholesterolemia/hyperlipidemia; Merck & Co.'s Gardasil 9 vaccine against human papillomavirus (HPV) infection; Otsuka Pharmaceutical and Lundbeck's brexpiprazole for schizophrenia and depression; Sanofi's Toujeo (new-formulation insulin glargine) for diabetes; and Novartis' Cosentyx (secukinumab) for psoriasis and psoriatic arthritis.

The report goes on to say, "Key trends to watch in 2015 are the rise of immuno-oncology approaches for treating cancer, the race to be the next big cholesterol drug, the entry of a first-in-class heart failure drug, and the entry of more convenient all-oral regimes for HCV. Opdivo versus Keytruda is the race to watch in the immuno-oncology space, while Praluent and evolocumab battle it out in the cholesterol field, LCZ-696 aims to make its mark for heart failure, and Gilead, AbbVie and Merck compete to win space in the HCV market." It concludes that far more blockbusters will enter the market this year than in 2014.
About the Author
  • Ilene Schneider is the owner of Schneider the Writer, a firm that provides communications for health care, high technology and service enterprises. Her specialties include public relations, media relations, advertising, journalistic writing, editing, grant writing and corporate creativity consulting services. Prior to starting her own business in 1985, Ilene was editor of the Cleveland edition of TV Guide, associate editor of School Product News (Penton Publishing) and senior public relations representative at Beckman Instruments, Inc. She was profiled in a book, How to Open and Operate a Home-Based Writing Business and listed in Who's Who of American Women, Who's Who in Advertising and Who's Who in Media and Communications. She was the recipient of the Women in Communications, Inc. Clarion Award in advertising. A graduate of the University of Pennsylvania, Ilene and her family have lived in Irvine, California, since 1978.
You May Also Like
SEP 15, 2019
Immunology
SEP 15, 2019
What We Don't Know Won't Hurt Us, Right?
A review in Frontiers in Pediatrics describes a common food additive that could both create and trigger autoimmune attacks, calling for warnings on food labels pending further tests....
SEP 15, 2019
Immunology
SEP 15, 2019
A Connection Between MS and Food Allergies
A correlation between food allergy and inflammatory disease activity is observed by a team of researchers...
SEP 15, 2019
Health & Medicine
SEP 15, 2019
Toxic Air is Shortening Children's Lifespans
According to the State of Global Air 2019 report, air pollution is currently shortening life expectancy by an average of 20 months worldwide. This means th...
SEP 15, 2019
Immunology
SEP 15, 2019
The C-word. Michael Kinch's new book and the future of Cancer Treatment
The C-word. Dare we say it? Is a cure for cancer within reach?   Professor Michael Kinch https://publichealth.wustl.edu/scholars/michael-s-kinch/ of W...
SEP 15, 2019
Health & Medicine
SEP 15, 2019
Why does the flu virus thrive during winter?
If you’re one of the nearly 7 million people who suffered from influenza last season, you might be curious why the virus hits so much during winter m...
SEP 15, 2019
Microbiology
SEP 15, 2019
The Developing Fetus is Exposed to Bacteria in the Womb
Our bodies host many microbes, and scientists have been learning more about the role of this microbiome in our health, and when it is established....
Loading Comments...