JUN 19, 2022 3:45 PM PDT

Heart Disease and Diabetes Double Dementia Risk

WRITTEN BY: Annie Lennon

Having two or more cardiometabolic diseases, such as type 2 diabetes, heart disease, and stroke, may double dementia risk. The corresponding study was published in Alzheimer’s and Dementia.  

While cardiometabolic diseases taken individually are known to increase dementia risk, their simultaneous impact has been relatively less studied. In the present study, researchers thus sought to examine the effects of having more than one such condition at a time on cognitive function. 

To do so, they analyzed data from the Swedish National Study on Aging and Care, including 2,577 initially dementia-free participants aged 60 or older, and followed them for 12 years. Over the period, they analyzed patient health records for changes in cognitive function and evidence of dementia, alongside forms of cardiometabolic disease. 

In the end, they found that having more than one cardiometabolic disease doubled the risk for cognitive impairment and dementia and accelerated their development by two years. They further found the more metabolic diseases one had, the more likely they were to develop dementia.

However, they noted that those with just one cardiometabolic disease did not have a significantly higher risk of dementia. 

“This is good news. The study shows that the risk only increases once someone has at least two of the diseases, so it’s possible that dementia can be averted by preventing the development of a second disease,” said Abigail Dove, a doctoral student at the Aging Research Centre, part of the Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, and one of the study’s authors. 

“We should therefore focus on cardiometabolic disease prevention already in middle age, since the risk of cognitive failure and dementia appears higher among those who develop a cardiometabolic disease earlier in life,” she added. 

The researchers now hope to explore the mechanisms behind this link by investigating genetic factors and how cardiometabolic diseases exert changes in the brain. 

 

Sources: Neuroscience News, Alzheimer’s and Dementia

 

 

About the Author
University College London
Annie Lennon is a writer whose work also appears in Medical News Today, Psych Central, Psychology Today, and other outlets. When she's not writing, she is COO of Xeurix, an HR startup that assesses jobfit from gamified workplace simulations.
You May Also Like
JUL 01, 2022
Cannabis Sciences
Cannabis And Aging
JUL 01, 2022
Cannabis And Aging
How does cannabis affect our aging process? Does it accelerate it or slow it down?
JUL 20, 2022
Neuroscience
Stress Transmitter Wakes Up the Sleeping Brain Over 100 Times Per Night
JUL 20, 2022
Stress Transmitter Wakes Up the Sleeping Brain Over 100 Times Per Night
A study published in Nature Neuroscience reported that the stress hormone and transmitter noradrenaline wakes up the hum ...
JUL 23, 2022
Drug Discovery & Development
Antibiotics Affect Gut Microbiome of Male and Female Rats Differently
JUL 23, 2022
Antibiotics Affect Gut Microbiome of Male and Female Rats Differently
Antibiotics induce sex-specific effects on the gut microbiome of male and female rats. The corresponding study was publi ...
JUL 27, 2022
Neuroscience
What is Trigeminal Neuralgia?
JUL 27, 2022
What is Trigeminal Neuralgia?
Trigeminal neuralgia is an extremely painful disorder that usually impacts the lower face and jaw, but may also involve ...
AUG 04, 2022
Clinical & Molecular DX
Artificial Intelligence Shows Promise in Diagnosing Strokes
AUG 04, 2022
Artificial Intelligence Shows Promise in Diagnosing Strokes
Quick identification and intervention is critical in successfully treating a stroke. During a stroke, blood supply to th ...
AUG 10, 2022
Health & Medicine
Blood Vessel Disease May Worsen Cognition in Alzheimer's Disease
AUG 10, 2022
Blood Vessel Disease May Worsen Cognition in Alzheimer's Disease
A new study from a group of Alzheimer’s disease researchers at Augusta University is highlighting the importance o ...
Loading Comments...