AUG 19, 2018 03:39 AM PDT

Clay-Based Technology Helps Form Blood Vessels

WRITTEN BY: Nouran Amin

Angiogenesis is the biological process of forming new blood vessels.

The process of angiogenesis serves as one of the major clinical challenges in wound healing and tissue implants. Scientists at Texas A&M University have sought to address this clinical issue by developing clay-based technology that will seek to assist in the process of angiogenesis by delivering therapeutic proteins.

The research team, led by members of the Inspired Nanomaterials and Tissue Engineering Lab in the Department of Biomedical Engineering, have designed this technology that introduced a new type of two-dimensional clay known as nanosilicates. The nanosilicates will seek to deliver multiple specialized proteins known as growth factors into the body in order to stimulate new blood vessel formation. According to biomedical engineering assistant professor, Dr. Akhilesh K. Gaharwar, the clay is designed to lengthen the release through its high surface area and charged characteristics allowing blood vessels time to form. "Clay nanoparticles work like tiny weak magnets that hold the growth factors within the polymeric hydrogels and release very slowly," Gaharwar said. "Sustained and prolonged release of physiologically relevant doses of growth factors are important to avoid problems due to high doses, such as abrupt tissue formation."

Image Credit: Agora Media via

Additionally, Dr. Kayla Bayless, a co-investigator of the study from the Department of Molecular and Cellular Medicine, explains that the clay maintains the organization of the growth factors, prevents abnormal growth, and moderates the activity of surrounding cells. Gaharwar also believes that establishing clay nanoparticles as the platform technology for therapeutic delivery, then the research will greatly impact the future of bioactive scaffolds and implants.

The research study was published in Advanced Biosystems and funded by the Division of Chemical, Bioengineering, Environmental and Transport Systems of the National Institute of Science, the National Institute of Biomedical Imaging, and Bioengineering of the National Institutes of Health and by the National Science Foundation.

Source: Texas A&M University

About the Author
  • Nouran enjoys writing on various topics including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
SEP 14, 2018
Earth & The Environment
SEP 14, 2018
How neural networks can help us understand clouds and climate change
A new study published in the Proceedings of the National Academy of Sciences takes a fresh look on just how much clouds are impacting climate models. While...
SEP 16, 2018
SEP 16, 2018
3D Virtual Stimulation Detects Irregular Heartbeats
According to a study published in Nature Biomedical Engineering, researchers at Johns Hopkins University have performed 3D personalized virtual simulations...
SEP 18, 2018
Cell & Molecular Biology
SEP 18, 2018
Visualizing the Organization of Human Cells With Machine Learning
Instead of fluorescent labeling, scientists found a way to use computers to identify cellular structures....
OCT 09, 2018
OCT 09, 2018
Predicting Autism With EEG?
Autism is a growing concern not only for parents and children but healthcare providers as well as researchers and public health officials. The latest numbe...
OCT 17, 2018
Space & Astronomy
OCT 17, 2018
Should We Build a Space Elevator?
Rockets are the primary means of sending cargo to and from space, but chemical burns are incredibly expensive, and this has some firms looking into alterna...
OCT 31, 2018
Health & Medicine
OCT 31, 2018
Small Animal Phobia and Virtual reality
Using digital technology for effective treatment of small animal phobia...
Loading Comments...