AUG 28, 2017 06:27 PM PDT

Melanoma and the Melanocyte Model

WRITTEN BY: Carmen Leitch

In this video from the Koch Institute at MIT, you can see work that won an Image Award for 2017. The image was generated by Dahlia Perez of the Lees lab, who explains her research. The lab studies how chemical cascades or pathways function in normal biology, and how they go wrong in disease. This picture is a part of an investigation of melanoma in a zebrafish model.

Zebrafish have cells called melanocytes that are pigmented with melanin. These cells are seen in the image in black along with another type of pigmented cell that is yellow. These cell types give zebrafish their coloration. The melanocytes are also the origin of melanoma.

There are two types of genetic mutations associated with melanoma, one of the skin and one of the eye. But treatments for melanoma that impacts the skin don't work for that of the eye. The human mutations were put into the zebrafish genome (and designed to affect the melanocytes only), to observe the impacts. This work can help reveal more about how to treat different types of melanoma.
About the Author
  • Experienced research scientist and technical expert with authorships on 28 peer-reviewed publications, traveler to over 60 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
NOV 20, 2019
Plants & Animals
NOV 20, 2019
North American Bird Populations Fell 29% Over 50 Years, But is it Too Late?
Birds are often at the forefront of interest when it comes to wildlife enthusiasts and photographers. Sadly, new scientific research suggests that bird pop...
NOV 20, 2019
Plants & Animals
NOV 20, 2019
Watch a Pod of Dolphins Play Catch With a Pufferfish
Playing catch with a ball of some sort is a popular past time for humans, but as it would seem, even dolphins might enjoy partaking in similar behaviors. I...
NOV 20, 2019
Cardiology
NOV 20, 2019
New Study Sheds Lights On Fat Formation
At normal levels, white fat tissue is known as the body's energy storage unit. When this type of tissue over accumulates, it begins to disrupt several ...
NOV 20, 2019
Cardiology
NOV 20, 2019
Parkinson's Disease is Present in the Blood
Parkinson's disease is a progressive disorder of the nervous system. Often starting with a barely noticeable tremor in one hand, the disease affects a...
NOV 20, 2019
Plants & Animals
NOV 20, 2019
What Makes Cheetahs Such Adept Predators?
The humble cheetah has earned its reputation as the world’s fastest land animal. This large cat is capable of accelerating to speeds of up to 60 mile...
NOV 20, 2019
Plants & Animals
NOV 20, 2019
Watch a Sunfish Get a Cleaning in the Depths of the Ocean
Ocean sunfish, also known as Mola Mola, are the world’s heaviest bony fish. These creatures can span up to three meters long and weigh more than two...
Loading Comments...