OCT 12, 2018 7:19 PM PDT

What is Next Generation Sequencing?

WRITTEN BY: Carmen Leitch

Our DNA is made up of four nucleotide bases: A, T, G, and C. The blueprints for creating an organism lie within the sequence of those bases, and for decades now researchers have been sequencing the genomes of various organisms, including people. That process means figuring out the precise order of billions of those bases.

There are a variety of ways to sequence genetic material. A common method that has been around for many years is Sanger sequencing. Another more recent technology is next generation sequencing (NGS). Get an introduction to this technique from the video. 

Basically, in NGS millions of small pieces of the genome are sequenced at the same time, rather than trying to read it all in order. Bioinformatics techniques are then used to piece all of those fragments together; a large genome can thus be sequenced in less than a day.

About the Author
  • Experienced research scientist and technical expert with authorships on 28 peer-reviewed publications, traveler to over 60 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
MAR 30, 2020
Space & Astronomy
MAR 30, 2020
If Gravity Has Mass, This Could Explain Dark Energy
The Big Bang purportedly transpired 13.8 billion years ago, and even so, the universe continues to expand even today. Bu ...
APR 01, 2020
Health & Medicine
APR 01, 2020
Saliva Test can Measure THC Levels in Impaired Drivers
Now that cannabis products are legal in many states across the U.S., law officials need a quick and reliable way to test ...
APR 11, 2020
Clinical & Molecular DX
APR 11, 2020
Predecessors Of Periodontitis
Gingivitis is a mild periodontal disease that causes inflammation, irritation, redness, and swelling of the gingiva. Thi ...
APR 15, 2020
Chemistry & Physics
APR 15, 2020
Pandemic Maths: Why Time Doesn't Matter in Understanding Infection Trajectory
There's no doubt that a lot of our current attention goes to the COVID-19 infection cases, as media outlets publish ...
MAY 11, 2020
Space & Astronomy
MAY 11, 2020
Hear What Astronauts Think About SpaceX's Upcoming Crewed Launch
On Wednesday, May 27th, NASA will entrust commercial space company SpaceX with the coveted task of flying astronauts to ...
MAY 28, 2020
Chemistry & Physics
MAY 28, 2020
Expandable Resin Solves the Size Problem of 3D Printing
One of the current limitations of using a 3D printer is the size of the product. For someone to print a large part, they ...
Loading Comments...