OCT 12, 2018 07:19 PM PDT

What is Next Generation Sequencing?

WRITTEN BY: Carmen Leitch

Our DNA is made up of four nucleotide bases: A, T, G, and C. The blueprints for creating an organism lie within the sequence of those bases, and for decades now researchers have been sequencing the genomes of various organisms, including people. That process means figuring out the precise order of billions of those bases.

There are a variety of ways to sequence genetic material. A common method that has been around for many years is Sanger sequencing. Another more recent technology is next generation sequencing (NGS). Get an introduction to this technique from the video. 

Basically, in NGS millions of small pieces of the genome are sequenced at the same time, rather than trying to read it all in order. Bioinformatics techniques are then used to piece all of those fragments together; a large genome can thus be sequenced in less than a day.

About the Author
  • Experienced research scientist and technical expert with authorships on 28 peer-reviewed publications, traveler to over 60 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
SEP 17, 2018
Space & Astronomy
SEP 17, 2018
How Common Are Planetary Collisions?
Outer space is nothing short of a galactic free-for-all. Space rocks fly in virtually every direction, sporadically impacting larger objects like moons, pl...
SEP 20, 2018
Videos
SEP 20, 2018
The Lowdown on Vaccine Development and Production
Learn more about how vaccines are developed and tested, from the CDC....
SEP 27, 2018
Videos
SEP 27, 2018
Why haven't Tesla's solar roofs taken off yet?
In October of 2016, Tesla came out with prototypes of solar roof panels that were meant to revolutionize the way we think about producing energy for our ho...
OCT 11, 2018
Videos
OCT 11, 2018
How Iceland is growing forests for the first time in a millennium
Iceland is perhaps one of the worst cases of deforestation that the world has seen. Over the last 1,000 years, the country's forests have been felled f...
OCT 14, 2018
Videos
OCT 14, 2018
Globally, Many Students Are Over-Diagnosed With ADHD
When teachers notice issues with a student, parents naturally respond and often can lead to a diagnosis of ADHD. Now, a global study published in the Journ...
OCT 16, 2018
Videos
OCT 16, 2018
Methane regulations for oil and gas could soon be reduced
The EPA has proposed loosening requirements for testing and repairing methane leaks in drilling operations for oil and gas w...
Loading Comments...