JUL 13, 2016 01:31 PM PDT

"Beyond the Red" - MIT Koch Institute Image Award Winner

WRITTEN BY: Carmen Leitch

Li Gu, a post-doctoral fellow, talks about his award-winning image in this video from MIT's Koch Institute. Gu works in the lab of in the lab of Paula Hammond and created this image in partnership with Xiangnan Dang, a post-doctoral fellow in Angela Belcher's lab.

Both laboratories use nanotechnology to detect and treat tumors, aiming to improve survival rates in cancer. In the image, green dots indicate the location of fluorescent particles in a metastatic tumor that is growing on a healthy liver.

They are using a technology called layer-by-layer to fuse near infrared II (NIR-II) fluorescent probes with nanoparticles. A negatively charged polymer encapsulates a NIR-II probe, and then, harnessing the power of electrostatic attraction, layers are built onto the particle. In the end, four layers sit on top of the near infrared core.

The particle they use can specifically target a tumor, and will thus colocalize with it. When a near-infrared light is shone onto the sample, the nanoparticle will emit fluorescent light indicating the location of the tumor.

The technology can allow researchers to put drugs or diagnostic agents onto a probe that will then direct things directly to the tumor - a so-called smart delivery system.
About the Author
  • Experienced research scientist and technical expert with authorships on 28 peer-reviewed publications, traveler to over 60 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
NOV 05, 2018
Videos
NOV 05, 2018
The Mechanisms Underlying the Deadly Blow of the Mantis Shrimp
The mantis shrimp packs a powerful punch that can strike its enemies with one of the fastest moves in the animal kingdom....
NOV 10, 2018
Videos
NOV 10, 2018
Engineering Viable Offspring From Same-sex Mouse Parents
Using a special kind of stem cell and genetic engineering, researchers have learned more about what's possible in reproduction....
NOV 11, 2018
Videos
NOV 11, 2018
The Island That Suddenly Disappeared
An island, consisting of a strip of gravel and sand and was important for the survival of beleaguered seals and sea turtles, has suddenly vanished after be...
NOV 22, 2018
Videos
NOV 22, 2018
The science of gratitude
On a day like Thanksgiving, it is easy to remember all that we are thankful for. But for a while now scientists have been trying to crack the code behind t...
NOV 26, 2018
Health & Medicine
NOV 26, 2018
A New Test for Fibromyalgia
Anyone who has experienced severe, chronic pain knows the long process it takes to get a correct diagnosis. Many people see an average of 5-6 specialists b...
DEC 15, 2018
Videos
DEC 15, 2018
The Near Perfect Memory
Hyperthymesia is an extremely rare neuropsychological condition. It is the condition of superior autobiographical memory characterized by the ability to re...
Loading Comments...