AUG 18, 2016 06:29 AM PDT

Finding Just The Right Dose


In the treatment of any kind of cancer, the goal is to stop, or at least significantly slow, the progress of the disease. Tumors survive because they have a blood supply, so researchers have looked for ways to starve tumors of their blood supply, essentially blocking the flow of blood as a roadblock stops traffic. At the Stephenson Cancer Center at the University of Oklahoma and the OU College of Pharmacy, researchers were given a grant of $792,000 to find ways to stop the progression of ovarian cancer. Estimates are that 22,000 women will be diagnosed with ovarian cancer this year and 14,000 of those women will die from the disease.

Most drugs that stop the tumor from signaling for new pathways for blood flow are very strong, but the body soon builds up a resistance to them and they soon become ineffective. The team at Stephenson is working to get the dose of these drugs to an "optimal level" that will stop the disease progression, but not create resistance. The plan on developing a sophisticated dosing system that includes laboratory analysis, complicated mathematical calculations, computational modeling and clinical validation. In addition to looking for new drugs, the computations of just the right dose will be a significant part of the research.
About the Author
  • I'm a writer living in the Boston area. My interests include cancer research, cardiology and neuroscience. I want to be part of using the Internet and social media to educate professionals and patients in a collaborative environment.
You May Also Like
JUL 08, 2018
Videos
JUL 08, 2018
They Say an Elephant Never Forgets...
They say an elephant never forgets, but is this really true? It’s a question that scientists have been trying to answer for ages, and as it turns out...
JUL 19, 2018
Videos
JUL 19, 2018
The Transition to Multicellular Life May Have Been Simple
It may have been relatively easy for complex organisms to form from one-celled microbes, researchers suggest....
JUL 24, 2018
Chemistry & Physics
JUL 24, 2018
How Does It Taste? Want Some Salt (and Microplastics)?
Looks can be very deceiving: pristine, pure-like grains of sea salt can be the perfect trojan horse for the invasion of the omnipresent environmental villa...
JUL 29, 2018
Space & Astronomy
JUL 29, 2018
Algae in Space: A Potential Food and Fuel Source?
During SpaceX’s recent CRS-15 launch, a mission to resupply the International Space Station with fresh supplies, the commercial space company’s...
AUG 02, 2018
Videos
AUG 02, 2018
CBD and THC Effects on the Brain
What has similar chemical make-ups but different structures? CBD and THC. In the video below, learn more about how THC (tetrahydrocannabinol) and CBD (Cann...
AUG 13, 2018
Videos
AUG 13, 2018
Some Ways of Healing the Brain Actually Damage It
Fixing the body usually involves “doing no harm” since that is part of the Hippocratic Oath doctors take. However, to repair the brain, sometim...
Loading Comments...