Professor Scott E. Fraser has a long-standing commitment to quantitative biology, applying the tools of chemistry, engineering, and physics to problems in biology and medicine. His personal research centers on imaging and molecular analyses of intact biological systems, with an emphasis on early development, organogenesis, and medical diagnostics. After training in physics (B.S., Harvey Mudd College, 1976) and biophysics (Ph.D., Johns Hopkins University, 1979), he joined the faculty at UC Irvine, and rose through the ranks to become Chair of the Department of Physiology and Biophysics. In 1990 he moved to Caltech to serve as the Anna L. Rosen Professor of Biology, and the Director of the Biological Imaging Center. He is deeply committed to interdisciplinary training and translational research, having helped found the Caltech Brain Imaging Center and the Kavli Institute of Nanoscience, as well as serving as the Director of the Rosen Center for Biological Engineering. In fall 2012, he moved to USC to take a Provost Professorship in the Dornsife College of Letters Arts and Sciences, the Children's Hospital Los Angeles, Keck School of Medicine and the Viterbi School of Engineering. He remains active in interdisciplinary research and serves as the Director of Science Initiatives for the USC campuses as well as co-directing USC's Bridge Institute with its Founding Director, Ray Stevens. A prolific author and inventor, Fraser has more than 240 peer-reviewed articles and more than 70 issued patents to his credit. He is the recipient of numerous honors and has been elected Fellow to the National Academy of Inventors, American Institute of Medical and Biological Engineers, American Academy of Arts and Science, American Association for the Advancement of Science, and the European Academy of Science.