NOV 04, 2016 10:00 AM PDT

Applying a multi-omics approach to tumor biomarker discovery - case studies

Sponsored by: Affymetrix, Affymetrix
Speakers
  • Assistant Professor, Department of Obstetrics, Gynecology & Reproductive Sciences; Yale School of Medicine
    Biography
      Dr. Yang Yang received her PhD degree from Nankai University. She is currently an Assistant Professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine.
    • Associate Professor of Pathology and Oncology; Johns Hopkins University School of Medicine
      Biography
        Dr. Tamara Lotan received her MD degree from the University of Chicago Pritzker School of Medicine. She is currently an Associate Professor of Pathology and Oncology at the Johns Hopkins University School of Medicine.
      • Professor of Pathology and Cell Biology; Columbia University
        Biography
          Dr. Antonia R. Sepulveda received her MD degree from University of Lisbon and her PhD degree from Baylor College of Medicine. She is Professor of Pathology and Cell Biology, Vice Chair for Translational Research, and Director, Division of Gastrointestinal Pathology at Columbia University.

        Abstract
        DATE:  November 4, 2016
        TIME:  10:00am PT, 1:00pm ET

        How do you develop clinically relevant biomarkers?

        Systematic tumor profiling with multi-omics tools and rapid analytical validation is a powerful way to discover clinically relevant biomarkers and increase the probability of success. The parallel analysis of any combination of SNP, copy number variation, gene expression and regulation, protein expression, or cellular analysis enables rapid identification of the most robust biomarkers for impactful clinical application. The data from one type of analyte can provide biological validation for another, enhancing the diagnostic power and increasing confidence in the final biomarkers selected towards routine clinical use.

        During this webinar, three translational researchers will:
        • Discuss their experience applying a multi-omics approach to tumor profiling in ovarian, pancreatic, and prostate cancers 
        • Demonstrate the use of advanced technologies enabling rapid efficient biomarker discovery and validation at the DNA, RNA, protein, and cellular levels
        • Explain how the Affymetrix Tumor Profiling Grant has allowed them to undertake important projects aimed at improving cancer treatment that otherwise would not have come to fruition
        • Answer your questions live during the broadcast!
        Learning Objectives:
        • Understand how a multi-omics approach can increase confidence in cancer biomarker discovery
        • Gain exposure to new translational research tools for whole-genome and whole-transcriptome profiling

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