JAN 12, 2023 10:00 AM PST

BioPharma 101: analysis of adeno-associated virus (AAV) vectors

Sponsored by: Sciex
C.E. Credits: P.A.C.E. CE Florida CE
Speakers

Abstract
Date:  January 12, 2023
Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET)
 
Adeno-associated viral vectors comprise the majority of recent gene therapy development programs due to their broad tissue-tropism and relatively low immunogenicity. Recent gene therapy approvals, including therapies for ocular and central nervous system disorders, have demonstrated AAV as an effective technology for genetic disease treatment. Biopharma 101 by SCIEX is intended to provide you with a thorough introduction to foundational analytical characterization workflows for AAV based gene therapeutics, from the basics of AAV production to assays for vector potency, immunogenicity, transduction effectiveness and packaging efficiency. Joining this class will upgrade your AAV gene therapy analytical expertise!
 
Learning Objectives
  • Characterize AAV protein impurities and determine accurate capsid titer
  • Determine genomic integrity, purity and titer with an accurate genome size estimation
  • Calculate the empty and full capsid ratio with an accurate determination of partial capsids
  • Observe nearly complete sequence coverage for the three viral proteins (VP1, VP2 and VP3) and confidently identify modifications in low abundance
 
 
Webinars will be available for unlimited on-demand viewing after live event.
 
Labroots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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