FEB 20, 2017 8:00 AM PST

Characterization of Biosimilars by SPR

Speaker

Abstract

Development of biosimilars for marketed bio-therapeutics is expected to increase patient access and affordability of these therapeutics within the healthcare system.  One of the key aspects of establishing biosimilarity at the analytical level is a comparative assessment of binding properties of the proposed biosimilar candidate and reference product. With a high level of sensitivity, and ability to measure kinetic parameters, Surface Plasmon Resonance (SPR) is an important analytical tool for characterizing binding properties of biological products. This presentation outlines strategies for biosimilar characterization utilizing various SPR methods. Challenges associated with day to day variability and statistical evaluation of data are summarized. Assay qualification efforts to make SPR assays more robust and repeatable, as well as solutions for better use of SPR as a part of biosimilar characterization are discussed.


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FEB 20, 2017 8:00 AM PST

Characterization of Biosimilars by SPR


Specialty

Biochemistry

Cancer Research

Systems Biology

Nutrition

Microbiology

Genotyping

Cancer Diagnostics

Live Cell Imaging

Microscopy

Pcr/rt-Pcr/real-Time Pcr

Microbiome

Infectious Disease

Dna Sequencing

Biomarkers

Next-Generation Sequencing

Geography

North America75%

Asia25%

Registration Source

Website Visitors100%

Job Title

Executive100%

Organization

Independent Laboratories25%

Academic Institution25%

Other25%


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