APR 12, 2018 1:30 PM PDT

Choosing the Right Fit: Navigating the Options for NGS Target Enrichment

Speaker
  • Product Marketing Manager, Target Enrichment, New England Biolabs
    Biography
      Andrew Barry is the Product Marketing Manager for Target Enrichment at New England Biolabs. He has a B.S. in Biology from Stonehill College, and Master of Science in Biomedical Engineering from Tufts University. Prior to joining NEB Andrew spent the first 10 years of his career at the Broad Institute of MIT and Harvard where he developed high-throughput processes for genomic applications. Following his time at the Broad, he joined Caliper Life Sciences (later acquired by PerkinElmer) where he held various positions in product management, strategic marketing, and R&D. Andrew joined New England Biolabs in 2016.

    Abstract

    Target enrichment offers several advantages over more comprehensive genomic profiling for a variety of scientific applications. The ability to selectively isolate specific genomic regions enables efficiencies in sequencing allowing greater depth of target coverage for higher sensitivity variant calling and inclusion of larger sample cohorts for improved power to drive scientific discovery. Drawbacks to target enrichment include complexities in sample processing through the variety of available approaches, high sample input requirements, and the inability to scale any technology across a broad range of target content.  During this webinar, we will explore these tradeoffs, and discuss novel approaches for selective enrichment of genomic targets.


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