Cris graduated in Medicine and Surgery from the University of Auckland in 1989 and began research while working as a house surgeon in Dunedin, NZ. A PhD in the University of Auckland led to a four-year postdoctoral fellowship in the Walter and Eliza Hall Institute in Melbourne, Australia before six years in Cambridge University, UK, where he was a Fellow of St Edmunds College and developed a deep interest in genomics and bioinformatics. While there he co-founded a bioinformatics company that became listed on the Tokyo stock exchange in 2007. In 2005 he returned to the University of Auckland where he leads a cross-disciplinary research team of clinicians, cell biologists and data scientists who use genomics, systems biology and bioinformatics to better understand human disease, especially cancer. He leads the Genomics Into Medicine Strategic Research Initiative in Auckland and Chairs the Auckland Regional Tissue Bank Scientific Advisory Board. He is a Deputy Chair of the NZ Institute of Environmental Science and Research (ESR) and a Principle Investigator in the Maurice Wilkins Centre. Previously, he served as President of the NZ Society for Oncology and was Director of the Bioinformatics Institute at the University of Auckland.