MAR 08, 2023 8:00 AM PST

Considerations to Limit Off-Target Edits in your Gene Editing Experiments


Event Date & Time
Date:  March 08, 2023
Time: 8:00am (PST),  11:00am (EST), 5:00pm (CET)
Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the genome to create cell-based disease models, animal models, and cell therapies for clinical implementation. These editing modalities can achieve high editing efficiencies in a wide range of different cell types and gene loci. However, this high editing efficiency comes at a price: Off target cleavage. Growing concerns for off-target editing and the downstream results of such edits have researchers looking for best practices in their genome editing experiments. In this presentation, we will explore strategies to limit off-target edits in your gene editing experiments, share considerations to take in different experimental scenarios, and demonstrate the efforts of Thermo Fisher Scientific to optimize the gene editing workflow - simplifying it for all researchers.
Learning Objectives
  • Summarize the impact of off-target edits in experiments
  • Discuss the methods to detect, identify, and limit off-target edits in your gene editing experiments
  • Assess solutions to streamline and improve the gene editing workflow
Webinars will be available for unlimited on-demand viewing after live event.
Labroots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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